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Found 1064 clinical trials
Cetuximab After Immunotherapy for the Treatment of Head and Neck Squamous Cell Cancer

This is a Phase II treatment, non-randomized, open label clinical trial to study the efficacy of the Cetuximab when administered as single agent in recurrent/ metastatic head and neck squamous cell carcinoma after the failure or intolerance of immuno-oncology or immuno-oncology combined with chemotherapy.

squamous cell carcinoma of head and neck
metastatic head and neck squamous cell cancer
head and neck cancer
squamous cell carcinoma
cetuximab
  • 0 views
  • 19 Feb, 2024
  • 1 location
Microlearning-Based Health Education for Ambulatory Surgery Patients  

Participants will be patients scheduled for either a mid-urethral sling procedure or a vaginal hysterectomy, and they will complete pre- and post-education surveys as part of the study.

  • 0 views
  • 28 Oct, 2025
  • 1 location
Effect of Ketone Esters in Parkinson's Disease

Ketones esters have shown to improve mitochondrial function and are currently use to enhanced functional performance. As Mitochondrial dysfunction is one of the proposed mechanism of neuronal injury in Parkinson's disease, the study aims to assess the tolerability,side effects and effect of oral ketone esters in Patients with Parkinson's disease.

parkinson's disease
  • 0 views
  • 19 Feb, 2024
  • 1 location
Early Use of Airway Pressure Release Ventilation (APRV) in ARDS

Airway pressure release ventilation (APRV) is a time-cycled, pressure controlled, intermittent mandatory ventilation mode with extreme inverse I:E ratios. Currently it is considered as a non-conventional ventilatory mode. The investigators aim to compare APRV with conventional mechanical ventilation (MV) in patients with acute respiratory distress syndrome (ARDS).

intermittent mandatory ventilation
airway pressure release ventilation
fraction of inspired oxygen (fio2)
acute respiratory distress
FIO2
  • 0 views
  • 19 Feb, 2024
  • 1 location
GutMe!: IBS and Collagen Protein Powder an Interventional Study

In this study we would like to understand how or if a food-based supplement affects gut symptoms such as bloating, stomach cramps and irregular bowel habits. Through using a digital symptom tracking app for a few weeks, you may just learn more about exactly what is triggering your symptoms!

spasm
bloating
gut symptoms
  • 0 views
  • 19 Feb, 2024
  • 1 location
Neoadjuvant T-VEC in High Risk Early Melanoma

Our ability to predict non-responder from responder to immunotherapeutic agents such as T-VEC is not yet defined and the risk of universal exposure to these systemic agents may outweigh the hypothesized benefit given the potential for immune-mediated toxicity as well as associated costs.

hepatitis
melanoma stage
advanced melanoma
tubal ligation
karnofsky performance status
  • 0 views
  • 19 Feb, 2024
  • 1 location
Initial Attack on Latent Metastasis Using TAS-102 for ct DNA Identified Colorectal Cancer Patients After Curative Resection

This trial is a randomized, double-blind, multinational Phase III study to evaluate the efficacy and safety of preemptive treatment with FTD/TPI compared with administration of placebo as follow-up, which is the standard of care, in patients who underwent curative resection of colorectal cancer and then tested positive for ctDNA.

trifluridine/tipiracil
diarrhea
tas-102
colon cancer
colorectal adenocarcinoma
  • 0 views
  • 19 Feb, 2024
  • 37 locations
Safety and Effectiveness Assessment of the MakAir Artificial Ventilator

The objective of our study is to carry out an evaluation of the safety and the effectiveness of the use of the MakAir respirator as useful supplement in situation of shortage of technical devices of assistance to the mechanical invasive ventilation, related to COVID-19 through a protocol in 3 successive …

fraction of inspired oxygen (fio2)
acute respiratory distress
FIO2
respiratory distress
pao2
  • 0 views
  • 19 Feb, 2024
  • 2 locations
Nutritional Study of Fish Oil in Skin Quality in Healthy Women test 22222 (OPTIHUD)  

test sync --- The skin acts as a barrier against the external environment and prevents water loss from the body. Aging is a natural process leading to changes in the skin and fish oil has been shown to prevent inflammation, hyperpigmentation and UV-damage.

Accepts healthy volunteers
  • 0 views
  • 19 Feb, 2024
  • 5 locations
Ipatasertib + Atezolizumab to Prevent Recurrence in TNBC

The purpose of this study is to determine if a combination of two drugs ipatasertib and atezolizumab works as a treatment for residual cancer in the breast or lymph nodes and have circulating tumor DNA in the blood. This research study involves the following investigational drugs: Ipatasertib Atezolizumab

invasive breast cancer
serum bilirubin
atezolizumab
breast cancer
bisphosphonate
  • 0 views
  • 19 Feb, 2024
  • 1 location