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Found 49 clinical trials
Immunogenicity and Safety Study of a Quadrivalent Meningococcal Conjugate Vaccine When Co-administered With Routine Pediatric Vaccines in Healthy Infants and Toddlers in Europe

The primary objective of the study is to demonstrate the non-inferiority of the antibody response against meningococcal serogroups A, C, Y, and W following a 3-dose series of MenACYW conjugate vaccine compared to a 3-dose series of a licensed meningococcal vaccine when each vaccine is given concomitantly with routine pediatric …

conjugate vaccine
haemophilus
hepatitis b
genetic diseases
antibiotics
  • 0 views
  • 19 Feb, 2024
  • 29 locations
Study on a High-Dose Quadrivalent Influenza Vaccine Compared With Standard-Dose Quadrivalent Influenza Vaccine in Children 6 Months Through 35 Months of Age

The primary objective of the study is to compare the clinical efficacy of high-dose quadrivalent influenza vaccine (QIV-HD) to standard-dose quadrivalent influenza vaccine (QIV-SD) in participants 6 months through 35 months of age for the prevention of laboratory-confirmed influenza illness caused by any influenza A or B type. The secondary …

flu symptoms
influenza
quadrivalent inactivated influenza vaccine
vaccination
hemagglutination inhibition
  • 0 views
  • 19 Feb, 2024
  • 9 locations
Study of a Pneumococcal Conjugate Vaccine When Administered Concomitantly With Routine Pediatric Vaccines in Healthy Toddlers and Infants  

Primary Objective: To assess the safety profile of each SP0202 formulation and Prevnar 13 in toddlers and infants (after each and any injection). To assess the immune response (serotype specific IgG concentration) of the SP0202 formulations and Prevnar 13 1 month after the administration of one dose in toddlers (Groups …

  • 0 views
  • 19 Feb, 2024
  • 31 locations
Evaluate the Efficacy Immunogenicity and Safety of 9-valent HPV Recombinant Vaccine in Chinese Healthy Females

This study is designed to evaluate the vaccine efficacy, immunogenicity and safety of the 9-valent Human Papillomavirus (Types 6, 11, 16, 18,31,33,45,52 and 58) Recombinant Vaccine (Hansenula Polymorpha) in Chinese Female Subjects Aged 20-45 Years .

cancer
cervical cancer
gardasil
flushed skin
emergency contraception
  • 0 views
  • 19 Feb, 2024
The Effect of Inflammation and Damage to Lymph Node Structures on Durable Protective Immunity Following Vaccination

This protocol will study yellow fever vaccine (YFV) in two cohorts of people, one from Uganda and the other from Minnesota where we collect lymphoid tissues (LT) and peripheral blood monocytes (PBMCs) before and after vaccination using a new technique to catalog infectious burden of the individual, determine the relationship …

vaccination
immunosuppressive
yellow fever
  • 0 views
  • 19 Feb, 2024
Study of Late Fetal Loss in Poitou-Charentes. GYNE-COVID

If the maternal-fetal transmission of COVID 19 is confirmed and that it is responsible for obstetric complications, a preventive action could be proposed to the patients by the preconception vaccination. The investigators are seeking to clarify the frequency of this transmission is information awaited by caregivers, women, couples in particular …

  • 0 views
  • 19 Feb, 2024
Strength for U in Relationship Empowerment

The objective of this study is to test whether the innovative intervention, "Strength for U in Relationship Empowerment" (SURE), reduces the frequency of IPV more than an attention, time, and information matched control condition in perinatal women seeking mental health care.

drug use
  • 0 views
  • 19 Feb, 2024
Clinical Study of an Dendritic and Glioma Cells Fusion Vaccine With IL-12 for Treatment-na ve GBM Patients.

A multi-center, open-label, single-arm, phase I/II clinical study is designed to test the safety and immunogenicity of an investigational Dendritic and Glioma Cells Fusion vaccine given with IL-12 for treatment-nave patients after resection of glioblastoma.

glioma
blood cell count
glioblastoma multiforme
temozolomide
white blood cell count
  • 0 views
  • 19 Feb, 2024
A Study of COVID 19 Convalescent Plasma in High Risk Patients With COVID 19 Infection

Purpose of Study The purpose of this study to evaluate, the effectiveness of convalescent plasma in combatting the symptoms and effects of the coronavirus disease, COVID-19. Beyond supportive care, there are no proven treatment options for COVID-19.

FIO2
chest x-ray
x-rays
coronavirus infection
fraction of inspired oxygen (fio2)
  • 0 views
  • 19 Feb, 2024
A Study to Evaluate the Safety Reactogenicity and Immunogenicity of Vaccine CVnCoV in Healthy Adults

This study aims to evaluate the safety and reactogenicity profile after 1 and 2 dose administrations of CVnCoV at different dose levels.

vaccination
tubal occlusion
acute respiratory syndrome (sars)
estrogen
inhibition of ovulation
  • 0 views
  • 19 Feb, 2024