Found 36643 clinical trials
Prevalence of Obstructive Sleep Apnea Hypopnea Syndrome (OSAHS) Following Squamous Cell Carcinomas of the Oropharynx Treatment by Combined Chemoradiotherapy
The study's aim is to determinate the prevalence of obstructive sleep apnea hypopnea syndrome after treatment by combined chemoradiotherapy in a locally advanced stages treated population of oropharyngeal cancer. Indeed, the level of knowledge about the consequences of oropharyngeal cancer treatment on sleep quality remains poor but the few studies …
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- 19 Feb, 2024
Cancer Therapy Effects on the Heart
Anthracycline chemotherapies (e.g. doxorubicin, daunorubicin) is commonly given to treat pediatric cancer, and carries a risk of cardiotoxicity. Over the long term, children who receive these therapies have an increased risk of heart failure and early cardiovascular death.
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- 19 Feb, 2024
Evaluating Cascade Communication Methods
Hereditary cancer programs face challenges with respect to effective communication of genetic test results within families and uptake of genetic testing by relatives.
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- 19 Feb, 2024
Monitoring of Metabolic Adverse Events of Second Generation Antipsychotics in a Naive Pediatric Population
Introduction: Second Generation Antipsychotics (SGAs) are widely used in the pediatric population. It is currently established that SGAs may induce undesirable metabolic adverse events (AEs) such as weight gain, metabolic changes in blood lipids or glucose with risk of potential cardiovascular morbidity and mortality. The Canadian Alliance for Monitoring Effectiveness …
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- 19 Feb, 2024
ABCB1/P-glycoprotein Expression Influence on Non-metastatic Osteosarcoma of the Extremities
The histological response to primary chemotherapy will be expressed as a percentage of tumor necrosis. In the case of tumor necrosis above 90% the patient is defined as a "good responder" in case of a lower percentage as a "poor responder".
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- 19 Feb, 2024
Neoadjuvant Chemotherapy in Borderline Resectable and Locally Advanced Pancreatic Cancer
This is a Norwegian prospective observational study that evaluates the resectability rate in patients with borderline resectable and locally advanced pancreatic cancer who received neoadjuvant chemotherapy in a population based cohort. Eligible patients are treated with neoadjuvant chemotherapy possibly followed by surgical exploration and resection.
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- 19 Feb, 2024
The Effect and Mechanism of lncRNA NBR2 Regulating Endothelial Pyroptosis by Targeting GSDMD in Sepsis
The dysregulation of lncRNA results in the occurrence and development of tumors, diabetes, sepsis and other diseases. Therefore, we detected lncRNA and mRNA expression profile in 26 blood samples of septic patients using Arraystar LncRNA Microarray.
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- 19 Feb, 2024
Early Detection of Cardiac Damage by Two Dimensional Speckle Tracking Echocardiography After Thoracic Radiation Therapy
The purpose of this study is to detecte and predict early subclinical cardiac damage induced by thoracic radiation therapy based on twodimensional speckle tracking echocardiography combined with multiple circulating biomarkers.
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- 19 Feb, 2024
Risk Literacy Among Portuguese Medical and Dentistry Students
This study is an online survey to assess risk literacy among students of the medical and dentistry faculties in Portugal. Risk literacy is the capability to understand and interpret statistical information, based on simple rules of thumb. The investigators assess the level of "medical risk literacy" among Portuguese medical and …
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- 19 Feb, 2024
Skin-to-skin Contact in Neonatal Intensive Care Unit (NICU) Caregiving Touch and Neural Correlates of Slow Stroking Touch in Preterm Infants
Preterm (PT) infants spend their first weeks of life in Neonatal Intensive Care Unit (NICU) where receive little affective physical contact, which plays a crucial role in brain development. Evidence indicates that skin-to-skin contact (SSC) has a positive effect on infants' neurophysiological and behavioral adjustment to postnatal life. Moreover, caregiving …
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- 19 Feb, 2024