Found 36643 clinical trials
Patient-Derived Xenografts to Reduce Cancer Health Disparities
This trial establishes patient-derived cancer xenografts in addressing cancer health and treatment disparities that disproportionately affect racial/ethnic minorities. Understanding the genetic and response differences among racial/ethnic minorities may help researchers enhance the precision of therapeutic treatments.
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- 19 Feb, 2024
Locoregional Surgery of the Primary Tumor in de Novo Stage IV Breast Cancer Patients
Current guidelines lack definitive evidences about the relative benefits of locoregional surgery for the primary tumor in de novo stage IV breast cancer. The aim of this study (SYSBTC-001) was to investigate the role of locoregional surgery for primary tumor in de novo stage IV breast cancer.
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- 19 Feb, 2024
Preclinical Project on the Traitment of Acute Lymphoblastique Leukemia With NVP-BEP800 an Inhibitor of the Heat Shock Protein HSP90
NVP-BEP800, a new HSP90 inhibitor, has particularly interesting therapeutic potential and represents hope in cancer pathologies. While it is currently being tested for solid cancers, no preclinical study has yet demonstrated its effectiveness in acute lymphoblastique leukemia (ALL).
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- 19 Feb, 2024
A Longitudinal Observational Biomarker Study in Pancreatic Cancer Patients Receiving Chemotherapy
Based on the literature, the pancreatic cancer treatment predictor biomarker, which is used in the domestic clinical field, is actually applied to the pancreatic cancer patient cohort of the National Cancer Center.
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- 19 Feb, 2024
Feasibility of Non-Operative Management of Rectal Cancer in a Rural Population
This is an observational research study. Patients with rectal cancer can choose different courses of treatment. This study will follow these patients over the course of approximately six years, depending on their treatment.
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- 19 Feb, 2024
Radiomics-based Artificial Intelligence System to Predict Neoadjuvant Treatment Response in Rectal Cancer
In this study, investigators utilize a radiomics prediction model to predict the tumor response to neoadjuvant chemoradiotherapy (nCRT) before the nCRT is administered for patients with locally advanced rectal cancer (LARC).
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- 19 Feb, 2024
RadioPathomics Artificial Intelligence Model to Predict nCRT Response in Locally Advanced Rectal Cancer
In this study, investigators utilize a radiopathomics integrated Artificial Intelligence (AI) supportive system to predict tumor response to neoadjuvant chemoradiotherapy (nCRT) before its administration for patients with locally advanced rectal cancer (LARC).
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- 19 Feb, 2024
Prospective Trial for the Evaluation of Radiogenomics in Advanced Rectal Cancer
In patients with advanced rectal cancer, molecular subtypes will be identified by preoperative biopsy, CT, MRI / PET radiomics analysis, clinical features, and clinical features will be confirmed and compared.
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- 19 Feb, 2024
Influence of Hormone Treatment in Radiation Therapy for Bladder Cancer
Bladder cancer is often treated with cystectomy or radiation therapy. Following radiation therapy patients will often have severe side effects from the treatment.
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- 19 Feb, 2024
The Real World Study of Neoadjuvant Immunotherapy in Early Stage NSCLC in China
Several published clinical trials have shown the superiority of immunotherapy in neoadjuvant setting. Here we conducted this real world study to see whether neoadjuvant immunotherapy would bring MPR and survival benefits in NSCLC, for example, single agent immunotherapy or immunotherapy combination with chemotherapy. Furthermore biomarker analysis would be also performed …
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- 19 Feb, 2024