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Found 36643 clinical trials
IBI3014 in Participants With Unresectable Locally Advanced or Metastatic Solid Tumors

This is a phase 1/2 multicenter, multi-regional, open-label, first-in-human study of IBI3014 in participants with unresectable locally advanced or metastatic solid tumors.

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  • 22 Aug, 2025
Strain vs. Left Ventricular Ejection Fraction-based Cardiotoxicity Prevention in Breast Cancer

Comparing preventive effect of myocardial global longitudinal strain-based cardioprotective stragety (angiotensin receptor blocker prophylaxis) with left ventricular ejection fraction-based strategy in breast cancer patients treated with adjuvant trastuzumab.

immunomodulators
her2+ breast cancer
trastuzumab
angiotensin
anthracyclines
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  • 19 Feb, 2024
Comparison of High-Dose Rate Brachytherapy and Stereotactic Ablative Radiotherapy as Monotherapy for the Treatment of Localized Prostate Cancer

Stereotactic ablative radiotherapy is an external beam radiation method that delivers large doses of radiation to the cancer in a short period of time, usually 5 treatments. This trial aims to find which of these two approaches is better in terms of patient-reported quality of life.

trus
adenocarcinoma of prostate
external beam radiation therapy
stage iib prostate cancer ajcc v8
androgen suppression
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  • 19 Feb, 2024
Radiotherapy Plus Nimotuzumab or Cisplatin in Nasopharyngeal Carcinoma

This is a phase III randomized clinical trial of definitive radiotherapy plus EGFR blocker nimotuzumab versus radiotherapy plus cisplatin(CCRT) for nasopharyngeal carcinoma (NPC) patients with favorable response to induction chemotheray(IC), determining whether radiotherapy combined with nimotuzumab was non-inferior to CCRT and may provide new evidence for individualized comprehensive treatment of …

induction chemotherapy
nimotuzumab
renal function test
epstein-barr virus dna
egfr blocker
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  • 19 Feb, 2024
Nedaplatin Versus Cisplatin in Treatment for Nasopharyngeal Carcinoma

To compare the effectiveness and toxicity of nedaplatin versus cisplatin in induction chemotherapy combined with concurrent chemoradiotherapy for locoregionally advanced nasopharyngeal carcinoma.

chemoradiotherapy
induction chemotherapy
fluorouracil
karnofsky performance status
renal function test
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  • 19 Feb, 2024
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  • 19 May, 2025
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  • 19 May, 2025
Niraparib/TTFields in GBM

Evaluating the efficacy and safety of niraparib and Tumor-Treating Fields (TTFields) in recurrent glioblastoma (GBM).

glioblastoma
karnofsky performance status
renal function test
recurrent glioblastoma
niraparib
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  • 19 Feb, 2024
Chimeric Antigen Receptor (CAR) T Cells With a Chlorotoxin Tumor-Targeting Domain for the Treatment of MPP2+ Recurrent or Progressive Glioblastoma

Vaccines made from a gene-modified virus may help the body build an effective immune response to kill tumor cells.

malignant glioma
karnofsky performance status
immunohistochemistry
neutrophil count
leukapheresis
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  • 19 Feb, 2024
Thyroid Cancer and Photoacoustic Imaging

In addition, we would like to confirm the relationship between the results of photoacoustic imaging and histopathologic findings when thyroid nodules were diagnosed as thyroid cancer.

photoacoustic imaging
cancer
thyroid nodule
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  • 19 Feb, 2024