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Found 1041 clinical trials
Study of Nivolumab and Ipilimumab in Children and Young Adults With INI1-Negative Cancers

This clinical trial is studying two immunotherapy drugs (nivolumab and ipilimumab) given together as a possible treatment for INI1-negative tumors.

sarcoma
dyspnea at rest
pulse oximetry
hcg pregnancy test
chordoma
  • 0 views
  • 19 Feb, 2024
Two-Year Study of the Safety and Efficacy of the Second-Generation Tissue Engineered Vascular Grafts

A single arm clinical trial evaluating the safety and efficacy of the second generation TEVG as vascular conduits for extracardiac total cavopulmonary connection.

total cavopulmonary connection
  • 0 views
  • 19 Feb, 2024
Assessment of N-95 Facemask for Use in COVID-19 Pandemic in Case of Shortage of Personal Protective Equipment

The modified masks will be made from masks that are already available as well as filters available in the pulmonary department at the Oklahoma City VA Health Care System

coronavirus infection
covid-19
  • 0 views
  • 19 Feb, 2024
CPX-351 in Higher Risk Myelodysplastic Syndromes

Study of the efficacy of CPX-351 treatment in patients with higher risk myelodysplastic syndromes : as first line treatment or after hypomethylating agents failure

blood cell count
nephropathy
lenalidomide
cardiovascular disease
conjugated bilirubin
  • 0 views
  • 19 Feb, 2024
Cryoablation Atezolizumab/Nab-paclitaxel for Locally Advanced or Metastatic Triple Negative Breast Cancer

Drugs used in chemotherapy, such as nab-paclitaxel, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading.

metastatic triple-negative breast carcinoma
progesterone receptor
progesterone
estrogen receptor
curative surgery
  • 0 views
  • 19 Feb, 2024
Student-delivered Telehealth Program for COVID-19 Education and Health Promotion

The purpose of this study is to ensure effective health management among community-living older adults during unprecedented times, such as the current COVID-19 pandemic.

covid-19
  • 0 views
  • 19 Feb, 2024
Low Dose Ruxolitinib in Combination With Methylprednisolone

This study is to determine the efficacy and safety of combined Low dose Ruxolitinib With Methylprednisone as Initial Therapy for the aGVHD(acute graft-versus-host disease )

ruxolitinib
hematologic malignancy
tumorigenicity
acute graft-versus-host disease
regenerating islet derived protein 3
  • 0 views
  • 19 Feb, 2024
Home Blood Pressure Study for Recent Stroke Survivors With High Blood Pressure *On Hold Due to Global Pandemic*

The investigators hypothesize that hypertensive stroke survivors in the Washington, DC area who participate in the Home Blood Pressure Monitoring program will have a greater reduction in mean systolic blood pressure (SBP) from baseline to 3 months, as measured by automated office blood pressure (AOBP), as compared to usual care.

blood pressure management
systolic blood pressure
home blood pressure monitoring
hypertension
stroke
  • 0 views
  • 19 Feb, 2024
Restrictive Use of Dexamethasone in Glioblastoma

However, steroids are also linked to a multitude of adverse side effects that may affect survival of GBM patients such as major immunosuppression. The use of steroids during radiotherapy is associated with reduced overall- and progression-free survival and has been identified as an independent poor prognostic factor.

dexamethasone
glioblastoma multiforme
neurologic symptoms
immunosuppression
  • 0 views
  • 19 Feb, 2024
A Study of the Biodistribution and Safety of [18F]GTP1 in Healthy Japanese Participants

The purpose of this study is to evaluate the biodistribution, safety and tolerability of a single dose of [18F]GTP1 as a tau targeted radiopharmaceutical in healthy Japanese participants.

radiopharmaceuticals
  • 0 views
  • 19 Feb, 2024