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Found 296 clinical trials
The Effect of High Protein and Early Resistance Exercise Versus Usual Care in Critically Ill Patients (EFFORT-X Trial)

This is a 2-arm, parallel-group, randomized controlled trial that investigates the effect of combined high protein and early resistance exercise versus usual care on muscle mass, quality and strength, clinical outcomes, functional outcomes and quality of life in mechanically ventilated critically ill patients

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  • 19 Feb, 2024
Kinematic Assessment In Multiple Sclerosis

Multiple sclerosis (MS) affects more than a 120,000 people in the United Kingdom and is the commonest neurological condition in young adults. MS causes a number of symptoms including weakness, altered sensation, pain and memory difficulties. There are different forms of MS, including relapsing-remitting MS (RRMS), primary progressive MS (PPMS) …

multiple sclerosis
weakness
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  • 19 Feb, 2024
Respiratory Muscle Training (RMT) in ALS

Participants will be stratified into 2 groups based on baseline inspiratory muscle strength as determined by maximum inspiratory pressure (MIP): six participants with minimal to no respiratory weakness (i.e., MIP 70% predicted) and six participants with mild to moderate inspiratory weakness (i.e., MIP 40-70% predicted).

respiratory muscle training
maximum inspiratory pressure
weakness
maximum expiratory pressure
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  • 19 Feb, 2024
BCI-FES Therapy for Stroke Rehabilitation

Despite the best available physiotherapy, 30-60% of stroke survivors remain affected by difficulty walking, with foot weakness often being the main cause. Given that post-stroke gait impairments remain poorly addressed, new methods that can provide lasting improvements are necessary.

foot drop
stroke
ischemic stroke
spasticity
electrical stimulation
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  • 19 Feb, 2024
One-Year Quality of Life and Functional Prognosis of COVID-19 Patients in Post-ICU Setting

Therapeutic strategies implemented for the management of critically-ill patients may often lead to short-term muscular and functional alterations resulting in ICU-Acquired Weakness (ICUAW). These lead to long-term disabilities expressing trough dependence and quality of life impairment of survivors. The purpose of this study is to assess the quality of life, …

atrophy
covid-19
weakness
lung function
lung ultrasound
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  • 19 Feb, 2024
Acute Infection in Mitochondrial Disease: Metabolism Infection and Immunity During the COVID19 Pandemic

Background Mitochondrial disease is a rare disorder. It can cause poor growth, developmental delays, muscle weakness, and other symptoms. The disease is usually inherited. It can be present at birth or develop later in life. Infection is a major cause of disease and death in people with this disease.

rare diseases
diarrhea
mitochondrial diseases
vomiting
biochemical testing
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  • 19 Feb, 2024