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Found 77 clinical trials
Dupilumab for the Treatment of Moderate to Severe Chronic Hepatic Pruritus

To investigate the potential efficacy of dupilumab in the treatment of moderate to severe chronic hepatic pruritus.

dupilumab
chronic pruritus
  • 0 views
  • 19 Feb, 2024
Efficacy and Tolerability of Erenumab in the Management of Persistent Redness and Flushing in Rosacea

An exploratory open-label study of rosacea patients to study the efficacy and tolerability of erenumab in the prophylactic treatment of persistent redness and flushing attributed to rosacea. Approximately 30 subjects will be included in the study and receive erenumab 140 mg for three months. The study will begin June 2020 …

erythema
erenumab
headache
flushing
rosacea
  • 0 views
  • 19 Feb, 2024
Nutritional Study of Fish Oil in Skin Quality in Healthy Women test 22222 (OPTIHUD)  

test sync --- The skin acts as a barrier against the external environment and prevents water loss from the body. Aging is a natural process leading to changes in the skin and fish oil has been shown to prevent inflammation, hyperpigmentation and UV-damage.

Accepts healthy volunteers
  • 0 views
  • 19 Feb, 2024
  • 5 locations
Clindamycin and Triamcinolone in People With Glioblastoma to Prevent Skin-Related Side Effects of Tumor Treating Fields

The participants are being treated with Tumor Treating Fields (TTFields) for malignant glioma, and this type of treatment may cause skin-related side effects. This study will test whether using clindamycin and triamcinolone topical lotions can prevent skin-related side effects of TTFields.

triamcinolone
glioblastoma multiforme
malignant glioma
topical agents
glioma
  • 0 views
  • 19 Feb, 2024
Scar Resection and Reconstruction With Integra and Split Skin Grafts in Patients With Non-Suicidal Self-Inflicted Scars

Surgical resection with preservation of the subcutaneous tissue followed by consecutive reconstruction with a bilayer dermal regenerative matrix (IntegraTM) and split skin grafts might represent a promising and novel therapeutic approach. The hypothesis is that by surgically transforming the non-suicidal self-inflicted scars into a burn-like scar the patient's body and …

supportive psychotherapy
dermabrasion
scar
laser therapy
  • 0 views
  • 19 Feb, 2024
Can Additional Preoperative Skin Cleaning on Face Neck and Chest With Chlorhexidine Reduce Cutibacterium Acnes Contamination on Sutures in Arthroscopy Rotator Cuff Repair?

We hypothesized that preoperative skin cleaning on face, neck and chest with chlorhexidine can reduce C. acnes contamination on sutures in arthroscopic rotator cuff repair.

  • 0 views
  • 19 Feb, 2024
Cemiplimab Before and After Surgery for the Treatment of High Risk Cutaneous Squamous Cell Cancer

This phase I trial studies how well cemiplimab before and after surgery works in treating patients with high risk cutaneous squamous cell cancer. Immunotherapy with monoclonal antibodies, such as cemiplimab, may help the body's immune system attack the cancer, and may interfere with the ability of tumor cells to grow …

hair thinning
extranodal extension
heparin
hormone replacement therapy
monoclonal antibodies
  • 0 views
  • 19 Feb, 2024
Cohort of Patients With Systemic Sclerosis Within the Framework of the RESO Reference Centre

Systemic sclerosis (SSc) is a rare form of connective tissue disease characterized by vascular involvement and the intensity of fibrosis. The lack of available treatment is largely due to the very fragmented understanding of the pathophysiology of SSc. However, one of the keys to conducting quality research on this disease …

scleroderma
fibrosis
progressive systemic sclerosis
rheumatism
  • 0 views
  • 19 Feb, 2024
Neoadjuvant T-VEC in High Risk Early Melanoma

Despite the recent notable advances in the treatment of advanced melanoma with application of growing immunotherapies, patterns of response and factors resulting in treatment failure are poorly understood. Moreover, the application of these therapeutics has been limited in the neoadjuvant setting, particularly in earlier stage disease, even though this strategy …

cancer
platelet count
hepatitis
metastasis
systemic therapy
  • 0 views
  • 19 Feb, 2024
Pilot Study to Evaluate the Effect of Nicotinamide Riboside on Immune Activation in Psoriasis

They will have repeats of the screening tests. They will also have 2 skin biopsies. These will be from both lesions and unaffected areas. The areas will be injected with a numbing medicine. A round cutting device will remove small pieces of skin from each area.

nicotinamide
nicotinamide riboside
urine test
chronic inflammation
psoriasis
  • 0 views
  • 19 Feb, 2024