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Found 44 clinical trials
Mobile App as a Guide to Exercises for Patients With Chronic Stroke

Introduction: Stroke continues to be one of the leading causes of disability in the Spanish adult population with the presentation of impairments such as alteration of mobility and a consequent reduction in quality of life. These sequelae, generally chronic, generates a significant expense and saturation of social and health services. …

hemiplegia or hemiparesis
hemiplegia
physical rehabilitation
hemiparesis
stroke
  • 0 views
  • 19 Feb, 2024
Physiological Changes Induced Through MEP Conditioning in People With SCI

The study team is currently recruiting volunteers who are interested in participating in a brain-spinal cord-muscle response training study that aims to better understand the changes that take place in the nervous system as a result of this type of training. After spinal cord injury, brain-to-muscle connections are often interrupted. …

transcranial magnetic stimulation
traumatic brain injury
weakness
spinal cord injury
spinal cord
  • 0 views
  • 19 Feb, 2024
Doxapram Therapy in Preterm Infants (DOXA Trial)

AOP can lead to oxygen shortage and a low heart rate which might harm the development of the newborn, especially the central nervous system. In order to prevent oxygen shortage, infants are treated with non-invasive respiratory support and caffeine. Despite these treatments, many preterm newborns still suffer from AOP and …

apnea
off-label
mechanical ventilation
lung disease
pulmonary disease
  • 0 views
  • 19 Feb, 2024
A Study to Evaluate the Safety Tolerability and Immunogenicity of Tau Targeted Vaccines in Participants With Early Alzheimer's Disease

This study is a multicenter, double blind, randomized, placebo-controlled study to evaluate the safety, tolerability and immunogenicity of different doses, regimens and combinations of Tau targeted vaccines in participants with early Alzheimer's Disease.

acetylcholinesterase inhibitor
alzheimer's disease
dementia
mental state exam
mental state examination
  • 0 views
  • 19 Feb, 2024
CED of MTX110 Newly Diagnosed Diffuse Midline Gliomas

The blood brain barrier (BBB) prevents some drugs from successfully reaching the target source. Convection-Enhanced Delivery (CED) is a method of direct infusion of drugs under controlled pressure to the tumor that may reduce systemic side effects of drugs in the patient. The purpose of this Phase I study is …

dipg
glioma
platelet count
diffuse intrinsic pontine glioma
neutrophil count
  • 0 views
  • 19 Feb, 2024
Intervening With Opioid-Dependent MothersMothers and Infants

This study will assess the efficacy of the modified Attachment and Biobehavioral Catch-Up (mABC) Intervention, adapted for use with peripartum mothers receiving medication-assisted treatment for opioid use disorder. The investigators expect that mothers who receive the modified Attachment and Biobehavioral Catch-up Intervention will show more nurturing and sensitive parenting and …

opioid use disorder
opioid
narcotic use
  • 0 views
  • 19 Feb, 2024
Tipifarnib for the Treatment of Advanced Solid Tumors Lymphoma or Histiocytic Disorders With HRAS Gene Alterations a Pediatric MATCH Treatment Trial

This phase II pediatric MATCH trial studies how well tipifarnib works in treating patients with solid tumors that have spread to other places in the body (advanced), lymphoma, or histiocytic disorders that have HRAS genetic alterations. Tipifarnib may block the growth of cancer cells that have specific genetic changes in …

cns tumors
antineoplastic agents
autologous stem cell infusion
metastatic disease
anticancer agents
  • 0 views
  • 19 Feb, 2024
Effect of Brain Stimulation on Stepping Performance in Stroke Survivors and Healthy Adults

Participants are being asked to participate in a research study conducted by Shih-Chiao Tseng, PT, Ph.D. at Texas Woman's University. This research study is to determine whether low-intensive brain stimulation can enhance learning of a leg movement task. The investigators also want to know if brain stimulation can improve the …

traumatic brain injury
ischemic brain injury
chronic stroke
transcranial direct current stimulation
range of motion exercise
  • 0 views
  • 19 Feb, 2024
Minocycline in MS: Confirmation of Benefit

This is an open-label, single-arm clinical trial. Trial participants will include men and women, aged 18-60 years who have had a first demyelinating event within the previous 180 days and who have brain magnetic resonance imaging (MRI) with at least two brain T2 lesions which are at least 3 mm …

health screening
demyelination
mri brain
MRI
demyelinating disorder
  • 0 views
  • 19 Feb, 2024
French COVID Cohort

New infectious agents, such as the SARS, MERS and other novel coronavirus, novel influenza viruses, viruses causing viral haemorrhagic fever (e.g. Ebola), and viruses that affect the central nervous system (CNS) such as TBEV & Nipah require investigation to understand pathogen biology and pathogenesis in the host. Even for known …

middle east respiratory syndrome
mers
SARS
fever
antibiotics
  • 0 views
  • 19 Feb, 2024