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Found 43 clinical trials
Doxapram Therapy in Preterm Infants (DOXA Trial)

AOP can lead to oxygen shortage and a low heart rate which might harm the development of the newborn, especially the central nervous system. In order to prevent oxygen shortage, infants are treated with non-invasive respiratory support and caffeine. Despite these treatments, many preterm newborns still suffer from AOP and …

mechanical ventilation
pulmonary disease
doxapram
off-label
nervous
  • 0 views
  • 19 Feb, 2024
Mobile App as a Guide to Exercises for Patients With Chronic Stroke

Introduction: Stroke continues to be one of the leading causes of disability in the Spanish adult population with the presentation of impairments such as alteration of mobility and a consequent reduction in quality of life. These sequelae, generally chronic, generates a significant expense and saturation of social and health services. …

hemiplegia or hemiparesis
physical rehabilitation
stroke
hemiparesis
hemiplegia
  • 0 views
  • 19 Feb, 2024
A Study to Evaluate the Safety Tolerability and Immunogenicity of Tau Targeted Vaccines in Participants With Early Alzheimer's Disease

This study is a multicenter, double blind, randomized, placebo-controlled study to evaluate the safety, tolerability and immunogenicity of different doses, regimens and combinations of Tau targeted vaccines in participants with early Alzheimer's Disease.

acetylcholinesterase
mental state examination
alzheimer's disease
mild cognitive impairment
acetylcholinesterase inhibitor
  • 0 views
  • 19 Feb, 2024
CED of MTX110 Newly Diagnosed Diffuse Midline Gliomas

The blood brain barrier (BBB) prevents some drugs from successfully reaching the target source. Convection-Enhanced Delivery (CED) is a method of direct infusion of drugs under controlled pressure to the tumor that may reduce systemic side effects of drugs in the patient. The purpose of this Phase I study is …

platelet count
pediatric
anesthesia
glioma
neutrophil count
  • 0 views
  • 19 Feb, 2024
Intervening With Opioid-Dependent MothersMothers and Infants

This study will assess the efficacy of the modified Attachment and Biobehavioral Catch-Up (mABC) Intervention, adapted for use with peripartum mothers receiving medication-assisted treatment for opioid use disorder. The investigators expect that mothers who receive the modified Attachment and Biobehavioral Catch-up Intervention will show more nurturing and sensitive parenting and …

opioid
narcotic use
opioid use disorder
  • 0 views
  • 19 Feb, 2024
Tipifarnib for the Treatment of Advanced Solid Tumors Lymphoma or Histiocytic Disorders With HRAS Gene Alterations a Pediatric MATCH Treatment Trial

This phase II pediatric MATCH trial studies how well tipifarnib works in treating patients with solid tumors that have spread to other places in the body (advanced), lymphoma, or histiocytic disorders that have HRAS genetic alterations. Tipifarnib may block the growth of cancer cells that have specific genetic changes in …

rhabdomyosarcoma recurrent
recurrent childhood medulloblastoma
stem cell transplantation
HRAS
ascites
  • 0 views
  • 19 Feb, 2024
Effect of Brain Stimulation on Stepping Performance in Stroke Survivors and Healthy Adults

Participants are being asked to participate in a research study conducted by Shih-Chiao Tseng, PT, Ph.D. at Texas Woman's University. This research study is to determine whether low-intensive brain stimulation can enhance learning of a leg movement task. The investigators also want to know if brain stimulation can improve the …

transcranial direct current stimulation
brain stimulation
range of motion exercise
hemiparesis
chronic stroke
  • 0 views
  • 19 Feb, 2024
Minocycline in MS: Confirmation of Benefit

This is an open-label, single-arm clinical trial. Trial participants will include men and women, aged 18-60 years who have had a first demyelinating event within the previous 180 days and who have brain magnetic resonance imaging (MRI) with at least two brain T2 lesions which are at least 3 mm …

MRI
oligoclonal bands
demyelination
multiple symptoms
minocycline
  • 0 views
  • 19 Feb, 2024
French COVID Cohort

New infectious agents, such as the SARS, MERS and other novel coronavirus, novel influenza viruses, viruses causing viral haemorrhagic fever (e.g. Ebola), and viruses that affect the central nervous system (CNS) such as TBEV & Nipah require investigation to understand pathogen biology and pathogenesis in the host. Even for known …

fever
influenza
coronavirus infection
ebola virus disease
acute respiratory syndrome (sars)
  • 0 views
  • 19 Feb, 2024
Brain Health in the Time of COVID-19

This is a nationwide research program to study the neurological effects of COVID-19. It is open to the public. Healthy individuals and individuals who are or have been infected with COVID-19 are encouraged to join the effort. The study can be done at home with internet access and an iPad. …

  • 0 views
  • 19 Feb, 2024