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Found 223 clinical trials
DMT310-009 Topical in the Treatment of Acne Vulgaris

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  • The objective is to evaluate the tolerability, safety, and efficacy of DMT310 topical powder mixed with diluent in male and female patients with moderate to severe facial acne vulgaris
  • The objective is to evaluate the tolerability, safety, and efficacy of DMT310 topical powder mixed with diluent in male and female patients …

    • 0 views
    • 15 May, 2025
    Age-Related Macular Degeneration Benchmark Imaging Dataset (ABID)

    1000 participants from up to 25 international locations who are at least 50 years old with either healthy eyes or a diagnosis of Age-Related Macular Degeneration (AMD) will be consented to provide images of their eyes for a new dataset. This dataset is an important step in developing an Artificial …

    Accepts healthy volunteers
    • 0 views
    • 19 May, 2025
    Genetic Characteristics of Metastatic Breast Cancer Patients

  • At disease progression after 1st line treatment for MBC, blood sample (20cc) will be obtained (tissue; optional)
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    (2) WES, RNASeq, ctDNA, Exosome

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  • We will analyze genomic characteritics using WES, RNASeq, ctDNA, Exosome.
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    stage iv breast cancer
    breast cancer
    cancer
    • 0 views
    • 19 Feb, 2024
    Safety Pharmacokinetics and Preliminary Efficacy of Isatuximab in Patients Awaiting Kidney Transplantation

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    Secondary Objectives:

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  • Phase 2: To characterize the safety profile of isatuximab in kidney transplant candidates.

    kidney transplant
    chronic kidney disease
    diphenhydramine
    isatuximab
    nephropathy
    • 0 views
    • 19 Feb, 2024
    • 2 locations
    MTD Safety and Efficacy of NYH817G and NYH100P in Monotherapy and Combination in Patients With Advanced Solid Tumors

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    • 0 views
    • 19 Feb, 2024
    Cervical Ripening Balloons for Same-Day Cervical Prep (CRB)

  • How acceptable is cervical preparation with cervical ripening balloon for same-day outpatient D&E?
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    Participants will:

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  • Have cervical preparation with cervical ripening balloon (experimental group) or osmotic dilators (usual care group)
  • Complete two surveys, one about the cervical preparation and one about the D&E procedure
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    • 0 views
    • 12 May, 2025
    Dose De-escalation Study of the PI3k Alpha/Delta Inhibitor Copanlisib Given in Combination With the Immunotherapeutic Agents Nivolumab and Rituximab in Patients With Relapsed/Refractory Indolent Lymphoma

    Patients with relapsed or refractory follicular or marginal zone lymphoma who have received at least one prior line of therapy will receive

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  • Copanlisib IV: day 1, 8, 15 every 28 days
  • Nivolumab IV: Cycle 1 days 1 and 15; then day 1 only
  • Rituximab IV: Cycle 1 days …

    thyroiditis
    marginal zone lymphoma
    stem cell transplant
    central nervous system disease
    vasectomy
    • 0 views
    • 19 Feb, 2024
    Descriptive and Evaluation Study of the Use of Pulmonary Ultrasound in the Initial Management of Pregnant Women in the Context of COVID-19

    Objectives :

    Primary objective:

    To describe the lung ultrasound lesions in pregnant women in case of suspected or confirmed COVID-19

    Secondary objectives:

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  • To compare the lung ultrasound lesions with chest Computed Tomography -scanner (CT-Scan) lesions
  • To evaluate the performances of …

    • 0 views
    • 19 Feb, 2024
    A Study to Investigate the Pharmacokinetics and Safety of Dupilumab in Participants ≥6 Months to <18 Years of Age With Prurigo Nodularis

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    The total number of planned study visits for each participant will be 6.

    • 0 views
    • 14 May, 2025
    A Multinational Randomized Double-blind Placebo-controlled Study to Assess the Efficacy Pharmacodynamics Pharmacokinetics and Safety of Venglustat in Late-onset GM2

    Primary Objectives:

    Primary population (adult participants with late-onset GM2 gangliosidosis): To assess the efficacy and pharmacodynamics (PD) of daily oral dosing of venglustat when administered over a 104-week period

    Secondary population (participants with juvenile/adolescent late-onset GM2 gangliosidosis, GM1 gangliosidosis, saposin C deficiency, sialidosis type 1 or …

    • 0 views
    • 19 Feb, 2024
    • 2 locations