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Found 219 clinical trials
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  • 19 Feb, 2024
Cervical Ripening Balloons for Same-Day Cervical Prep (CRB)

  • How acceptable is cervical preparation with cervical ripening balloon for same-day outpatient D&E?
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    Participants will:

    <ul>
  • Have cervical preparation with cervical ripening balloon (experimental group) or osmotic dilators (usual care group)
  • Complete two surveys, one about the cervical preparation and one about the D&E procedure
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    • 0 views
    • 12 May, 2025
    Dose De-escalation Study of the PI3k Alpha/Delta Inhibitor Copanlisib Given in Combination With the Immunotherapeutic Agents Nivolumab and Rituximab in Patients With Relapsed/Refractory Indolent Lymphoma

    Patients with relapsed or refractory follicular or marginal zone lymphoma who have received at least one prior line of therapy will receive

    <ul>
  • Copanlisib IV: day 1, 8, 15 every 28 days
  • Nivolumab IV: Cycle 1 days 1 and 15; then day 1 only
  • Rituximab IV: Cycle 1 days …

    autologous hematopoietic stem cell transplant
    hepatitis b surface antigen
    psoriasis
    cyp3a4 inhibitors
    psychiatric disorder
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    • 19 Feb, 2024
    Descriptive and Evaluation Study of the Use of Pulmonary Ultrasound in the Initial Management of Pregnant Women in the Context of COVID-19

    Objectives :

    Primary objective:

    To describe the lung ultrasound lesions in pregnant women in case of suspected or confirmed COVID-19

    Secondary objectives:

    <ul>
  • To compare the lung ultrasound lesions with chest Computed Tomography -scanner (CT-Scan) lesions
  • To evaluate the performances of …

    • 0 views
    • 19 Feb, 2024
    • 0 views
    • 14 May, 2025
    A Multinational Randomized Double-blind Placebo-controlled Study to Assess the Efficacy Pharmacodynamics Pharmacokinetics and Safety of Venglustat in Late-onset GM2

    Primary Objectives:

    Primary population (adult participants with late-onset GM2 gangliosidosis): To assess the efficacy and pharmacodynamics (PD) of daily oral dosing of venglustat when administered over a 104-week period

    Secondary population (participants with juvenile/adolescent late-onset GM2 gangliosidosis, GM1 gangliosidosis, saposin C deficiency, sialidosis type 1 or …

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    • 19 Feb, 2024
    • 2 locations
    Multicenter Perspective Study: Clinical Evaluation of the Persona MC With Preservation or Sacrifice of the PCL

    Primary endpoint

    -Evaluation of the survival of the implant after 5 years of follow-up

    Secondary endpoints

    <ul>
  • Evaluation of the survival of the implant at 10 years of follow up.
  • Evaluation of clinical and radiographic outcomes in Italian patients undergoing total knee replacement …

    avascular necrosis
    polyarthritis
    arthritis
    knee pain
    knee arthroplasty
    • 0 views
    • 19 Feb, 2024
    PROPHET Study: ctDNA-Guided Personalized Induction Immunochemotherapy for NSCLC (PROPHET)

    Researchers will use ctDNA dynamics to guide the cycles of induction treatment to see if some patients can avoid excessive cycles of treatment.--UATul>

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    • 19 May, 2025
    Intratumoral Tilsotolimod a TLR-9 Agonist Together With Intratumoral Ipilimumab and Intravenous Nivolumab in Patients With Advanced Cancers

    The trial will be divided into two parts:

    PART A:

    the first part will assess the safety of two regimen and will recruit patients with all types of injectable solid malignancies

    PART B:

    the second part will include 3 expansion cohorts of …

    tumor markers
    fluorouracil
    gilbert's syndrome
    irinotecan
    EGFR
    • 0 views
    • 19 Feb, 2024
    VARA (Virtual and Augmented Reality Applications in Rehabilitation): Motor Rehabilitation Protocol With GRAIL for Patients Affected by Hemiparesis

  • walking speed increase (but with the priority of the walking pattern)
  • increase in the resistance
  • Stregthening of the support reaction
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    hemiparesis
    weakness
    • 0 views
    • 19 Feb, 2024