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Found 82 clinical trials
Diagnostic Accuracy of the MADx Multi Array Xplorer (MAX 45k) Automated Laboratory System and the MADx Allergy Explorer Version 2 (ALEX ) - IgE Multiplex Test for the Diagnosis of Pre-defined Groups of Specific High-priority Allergens

Therefore, this clinical performance study is conducted to evaluate the diagnostic accuracy of the ALEX IgE multiplex test using the Multi Array Explorer (MAX 45k, MacroArray Diagnostics) automated laboratory system in comparison to a conventional IgE singleplex test system as well as clinical symptoms and skin prick test results in …

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  • 19 Feb, 2024
Skin Biophysical Measures for Assessing Head and Neck Cancer-Related External Lymphedema

Selected measurements in healthy persons of skin tissue dielectric constant as reference values for subsequent use to evaluate patients with head and neck lymphedema.

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  • 19 Feb, 2024
Sample Collection for Systems Evaluation of Patients With Unknown or Incompletely Characterized Immune Defects

These samples may be from biopsies, endoscopies, or other procedures. Some participants may have optional skin punch biopsies. For this, their skin is numbed. Then a tool removes 1 or 2 small pieces of skin from the forearm or thigh. Participants medical records will be checked to see if they …

gastrointestinal symptoms
dermatitis
autoimmune disease
endoscopies
episodic fever
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  • 19 Feb, 2024
GSD IX Natural History Study

Participant's medical charts will be continually reviewed for the duration of the study. If a liver, muscle or skin biopsy sample has been collected, a piece of the sample may be requested and stored for research purposes.

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  • 19 Feb, 2024
Observational Study in Diagnosed Patients COVID-19 Supported on an Outpatient Basis. (COVID-PSL)

Different symptoms may appear: fever, cough, asthenia, dyspnea, gastrointestinal forms, anosmia and / or ageusia, skin involvement, etc. Given the novelty of this infection, several questions remain: What are all the symptoms that can be contracted by a COVID-19 patient?

flu-like symptoms
fever
covid-19
respiratory disease
influenza
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  • 19 Feb, 2024
The Effects of Natural Sugars in Breast Milk on Healthy Infant Growth and Development

This study will investigate the effects of breastfeeding and breastmilk composition on infant gut microbiome development as well as obesity and cognitive outcomes. Breast milk contains certain natural sugars that can promote the growth of 'good' bacteria in the intestines and reduce the growth of harmful bacteria. The purpose of …

sugars
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  • 19 Feb, 2024
Smell and Taste Disorders in COVID-19 Patients

This is a prospective monocentric observational study with the aim of investigating the demographic and clinical factors related to the smell and taste disorders in patients with Severe Acute Respiratory Syndrome - Coronavirus - 2 (Sars-Cov-2) infection.

nasopharyngeal swab
acute respiratory syndrome (sars)
SARS
coronavirus infection
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  • 19 Feb, 2024
Tofacitinib for Immune Skin Conditions in Down Syndrome

People with Down syndrome (DS) display widespread immune dysregulation, including several immune skin conditions. This study hypothesizes that pharmacological inhibition of the increased interferon (IFN) signaling seen in DS is safe and could improve associated skin conditions.

vitiligo
atopy
tofacitinib
atopic dermatitis
hair thinning
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  • 19 Feb, 2024
Dupilumab for the Treatment of Moderate to Severe Chronic Hepatic Pruritus

To investigate the potential efficacy of dupilumab in the treatment of moderate to severe chronic hepatic pruritus.

chronic pruritus
dupilumab
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  • 19 Feb, 2024
Study of ATI-2138 in Adult Participants with Moderate to Severe Atopic Dermatitis

This is a Phase 2 open label study of ATI-2138 in participants with moderate to severe atopic dermatitis.

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  • 23 Jan, 2025
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