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Found 26 clinical trials
Epidemiological Study of the Microbiota in Critically Ill Children (n=100) From 1 to 16 Years Compared With Healthy Controls (n=50) and Its Relationship With Clinical Complications and Inflammatory Biomarkers

Objectives: To study the composition of the microbiota in critically ill children, and to know the relationship of its microbiota with clinical complications and inflammation biomarkers. Design: Multicenter observational and prospective study including 100 critically ill children admitted in three pediatric intensive care units with a prediction of more than …

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  • 19 Feb, 2024
Outcome of Patients Treated With ECLS

Extracorporeal life support (ECLS), also called extracorporeal membrane oxygenation (ECMO), is an extracorporeal technique of providing effective circulatory and (or) respiratory failure, with a growing number of critically ill patients benefit from it. The aim of this study is to investigate the outcome of patients treated With ECMO, and to …

respiratory failure
critically ill
critical illness
membrane oxygenation
extracorporeal membrane oxygenation
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  • 19 Feb, 2024
One-Year Quality of Life and Functional Prognosis of COVID-19 Patients in Post-ICU Setting

Respiratory failure is the main reason for admission in ICU of these patients. Therapeutic strategies implemented for the management of critically-ill patients may often lead to short-term muscular and functional alterations resulting in ICU-Acquired Weakness (ICUAW). These lead to long-term disabilities expressing trough dependence and quality of life impairment of …

lung function
weakness
respiratory failure
lung ultrasound
atrophy
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  • 19 Feb, 2024
Microbiota in COVID-19 Patients for Future Therapeutic and Preventive Approaches

The overarching aim of the present research proposal is to improve therapeutic strategies in critically ill patients with ARDS due to SARS-CoV-2 infection by advancing the pathophysiological understanding of this novel disease. This research thus focuses on inflammation, microcirculatory dysfunction and superinfection, aiming to elucidate risk factors (RF) for the …

endothelial dysfunction
critical illness
microbiota
inflammatory response
edta
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  • 19 Feb, 2024
COVID-19 Follow up Intensive Care Studies

Since the SARS-CoV-2 infection is relatively new, the long term attributable burden related to COVID19 has not been investigated yet. To date, in patients with COVID-19 and their family members, there is little information on the functional status, cognitive ability, pattern of return to work, and health related quality of …

acute respiratory syndrome (sars)
SARS
covid-19
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  • 19 Feb, 2024
Sequelae of Sars-CoV-2 Infections

By the end of 2019 a new coronavirus, named SARS-CoV-2, was discovered in patients with pneumonia in Wuhan, China. In the following weeks and months the virus spread globally, having a tremendous impact on global health and economy. To date, no vaccine or therapy is available. Severe courses of the …

acute respiratory syndrome (sars)
coronavirus infection
cardiovascular system
pneumonia
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  • 19 Feb, 2024