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Found 2,824 clinical trials

M Melanie Boltzmann, PhD

Prognostic Factors to Regain Consciousness

The study aims to identify factors that predict the medium and long-term outcome of patients with disorders of consciousness (DOC) undergoing early neurological rehabilitation. In this prospective, observational study, 130 DOC patients are going to be included (36 months). At study entry, different routine data, disease severity and functional status …

18-85 years All Phase N/A
U Ulrich Matt, MD, PhD

Sequelae of Sars-CoV-2 Infections

By the end of 2019 a new coronavirus, named SARS-CoV-2, was discovered in patients with pneumonia in Wuhan, China. In the following weeks and months the virus spread globally, having a tremendous impact on global health and economy. To date, no vaccine or therapy is available. Severe courses of the …

18 years and older All Phase N/A
B Björn Sjöstrom, M.D.

Prospective Observational Cohort Study of Critically Ill Patients With Covid-19 in Sweden

The study will prospectively collect data from patients with Covid-19 admitted to the Vsters Intensive Care Unit, Vsters Hospital. Demographic, clinical, radiographic and laboratory characteristics will be recorded. Analysis of data to identify predictors of disease severity, mortality and treatment response.

18 years and older All Phase N/A
P Philipp Buehler, MD

Microbiota in COVID-19 Patients for Future Therapeutic and Preventive Approaches

In light of the rapidly emerging pandemic of SARS-CoV-2 infections, the global population and health care systems are facing unprecedented challenges through the combination of transmission and the potential for severe disease. Acute respiratory distress syndrome (ARDS) has been found with unusual clinical features dominated by substantial alveolar fluid load. …

18 years and older All Phase N/A
G Gupta, Dr

Serial Tumour Biopsies and Blood Biomarkers in Melanoma

Recent advances in understanding how cancer develops and spreads have led to effective new treatments and improved outcomes for patients with melanoma. However, we know that these new treatments do not work for all patients: some do not respond to them and some initially respond but then develop resistance. The …

16 years and older All Phase N/A
M Matilde Zaballos, MD, PhD

Effects on the Qt Interval of COVID-19 Coronavirus Infection

The present study aims to evaluate the impact of COVID-19 disease and its treatment on ventricular repolarization, assessed by measuring the QTc interval, in patients admitted to the critical care unit.

18 years and older All Phase N/A
A Alain Gaffinel

Cardiac Arrest Incidence and Outcome Among Patients With COVID-19 in French ICUs

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is responsible for the novel coronavirus disease 2019 (COVID-19) pandemic. Among COVID-19 complications, in-hospital cardiac arrest (IHCA) was reported with a very poor outcome in a retrospective single-center study (0,7% of 30 days survival with good neurological outcome among IHCA patients with a …

18 years and older All Phase N/A
A Aliaa AR Hussein

Post COVID-19 Functional Status in Egypt

Since the outbreak of coronavirus disease - COVID-19 pandemic, most attention has focused on mode of transmission, clinical picture of the disease, treatment and prevention. In the coming weeks and months emphasis will gradually involve the post- acute care of COVID-19 survivors. It is anticipated that COVID-19 may have major …

100 years and younger All Phase N/A
P Peter Lüdike, MD

Prospective Analysis of the Feasibility of the PASCAL Spacer Technology for Transcatheter Mitral Valve Repair in an All-comers Cohort

To identify changes on mitral valve morphology and functionality by the application of the PascalTM in MR.

18 years and older All Phase N/A
M Michael Hultström, MD. PhD.

Follow-up of Critical COVID-19 Patients

The study will follow COVID-19 patients who required intensive care after 3-6 months and one year after discharge from the ICU with functional level as well as organ function to assess recovery after COVID-19. Blood and urine will be collected for biobanking.

18 years and older All Phase N/A

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