immunosuppressants Clinical Research Trials

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Found 271 clinical trials

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Phase 4
For adults
Recruiting in 10s
Interventional Study
all
Recruiting

Comparison of Tofacitinib and Methotrexate in Takayasu's Arteritis

The aim of this study is to evaluate and compare the efficacy and safety of tofacitinib and methotrexate based on prednisone therapy in patients with Takayasu arteritis

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19 Feb, 2024

Phase 2
For Seniors
For adults
Recruiting in 10s
Interventional Study
all
Dermatology
Recruiting

IVIG With Rituximab vs Rituximab as First Line Treatment of Pemphigus

Traditionally, treatment of pemphigus included high dose systemic corticosteroids with or without adjuvant immunosuppressants. However; the prolonged use of high dose steroids carries significant side effects. A recent randomized trial has proved the efficacy of Rituximab, a monoclonal anti-CD20 antibody against B-lymphocytes, as an efficacious therapy for pemphigus.

tositumomab

elisa

anti-cd20 antibody

immunomodulators

corticosteroids

0 views
19 Feb, 2024

Phase 2
For Seniors
For adults
Recruiting in 10s
Interventional Study
all
Recruiting

TPM Regimen (Thalidomide Prednisone and Methotrexate) in LGLL

Large granular lymphocytic leukemia (LGLL) is a lymphoproliferative disease, with LGL infiltration in peripheral blood and bone marrow, hepatosplenomegaly, and cytopenia. Both T-LGLL and CLPD-NK are indolent disease and share similar biology and clinical course, and treated under the same strategy. So the investigators put them together as LGLL. The …

t-cell large granular lymphocytic leukemia

prednisone

methotrexate

hepatosplenomegaly

leukemia

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19 Feb, 2024