cognitive changes Clinical Research Trials

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Found 252 clinical trials

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Phase 4
For Seniors
For adults
Recruiting in 1000s
Interventional Study
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Neurology
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Cognitive Outcomes After Dexmedetomidine Sedation in Cardiac Surgery Patients

Anesthesia is a drug induced, reversible, comatose state that facilitates surgery and it is widely assumed that cognition returns to baseline after anesthetics have been eliminated. However, many patients have persistent memory impairment for weeks to months after surgery. Cardiac surgery appears to carry the highest risk of postoperative cognitive …

postoperative cognitive dysfunction

coronary artery bypass graft

thoracotomy

cognitive deficit

cognitive impairment

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19 Feb, 2024

Optimized Tailored Interventions in Metabolic and Lifestyle Outcomes (OPTIMAL)

The goal of this clinical trial is to learn if increasing adherence to a Mediterranean-DASH Intervention for Neurodegenerative Delay (MIND) diet pattern improves brain and heart health relative to a healthy control diet in middle-aged adults. Our research team will evaluate three different groups: the first group will be chosen …

Accepts healthy volunteers

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19 May, 2025

For Seniors
For adults
Recruiting in 10s
Interventional Study
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Cognitive Changes and Neural Correlates After Rehabilitation of Masticatory Function in Elderly -an Intervention Study

Today in elderly tooth loss and loss of oral function is widespread, but it is an underexplored modifiable risk factor potentially contributing to the development of dementia. In this interventional study we want to investigate a "cause-effect" relationship between mastication and cognition in humans. A total of eighty (80) participants, …

prosthetic rehabilitation

dementia

mini-mental state examination

mental state examination

cognitive changes

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19 Feb, 2024