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Found 219 clinical trials
Natural History Study of Children and Adults With Neuroendocrine Neoplasms (NEN)s

Background Neuroendocrine neoplasms (NENs) are rare tumors that originate in neuroendocrine cells. NENs can affect almost any part of the body. People with low-grade tumors can live many years. But high-grade tumors can be very aggressive. Researchers want to learn more about this type of cancer. This may help them …

vasoactive intestinal polypeptide
somatostatin
glucagon
gastrin
positron emission tomography
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  • 19 Feb, 2024
Effects of Peri Partum Integrated Nursing Care Versus Routine Care in Placenta Previa : A Randomized Controlled Trail

At our institution, the annual number of placenta previa was 494 cases (1.7%); of whom 95 cases (19.2%) were proved to have a placenta accreta. Perioperatively, they are subjected to regular care of a tertiary university hospital. This study aims to determine the effectiveness of peri partum integrated nursing care …

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  • 19 Feb, 2024
Natural History Study of Children and Adults With Adrenocortical Cancer (ACC)

Background Adrenocortical cancer (ACC) is a rare tumor. The prognosis is very poor for people with advanced stages of ACC. Some people may live with ACC for years; others live for just months. Treatment options for ACC often do not work well. Researchers want to study the clinical course of …

adrenal
solid tumors
blood tests
adrenocortical carcinoma
cancer
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  • 19 Feb, 2024
Fecal Calprotectin Level in Patients With Nosocomial Diarrhea

Nosocomial diarrhea is a common problem.There are multiple ethiologies of nosocomial diarrhea in which can be divided into inflammatory and non inflammatory diarrhea. Fecal calprotectin is a good marker to identify inflammatory diarrhea in outpatient setting; for example, differentiating inflammatory bowel disease and irritable bowel syndrome. Its performance in inpatient …

fecal calprotectin
irritable bowel syndrome
diarrhea
inflammatory bowel disease
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  • 19 Feb, 2024
Serial Tumour Biopsies and Blood Biomarkers in Melanoma

Recent advances in understanding how cancer develops and spreads have led to effective new treatments and improved outcomes for patients with melanoma. However, we know that these new treatments do not work for all patients: some do not respond to them and some initially respond but then develop resistance. The …

metastatic malignant melanoma
blood test
cancer treatment
metastatic melanoma
advanced melanoma
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  • 19 Feb, 2024
Feasibility of Non-Operative Management of Rectal Cancer in a Rural Population

This is an observational research study. Patients with rectal cancer can choose different courses of treatment. This study will follow these patients over the course of approximately six years, depending on their treatment. Patients will be monitored through clinic visits and survey assessments to see how they do, how they …

proctectomy
rectal cancer
cancer
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  • 19 Feb, 2024
Trajectory of Microbiota Maturation in Healthy Bern Infants - a Network Approach

Background: Intestinal microbiota composition is fundamental to human health and undergoes critical changes within the first two years of life. Factors probably influencing the microbiota are the maternal microbiota and the general environment in Switzerland. However, the development of the intestinal microbiota is incompletely understood. Gaining knowledge of the trajectory …

mass spectrometry
microbiota
placenta
diabetes
hypertension
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  • 19 Feb, 2024
Pacing to Maintain Physiologic Ventricular Activation

Right ventricular pacing causes ventricular dyssynchrony and may be associated with impaired outcome. In the last decade, several approaches for more physiological pacing became available and were implemented in the latest guidelines. However, compared to conventional device implantation, cardiac resynchronization, His bundle pacing and left bundle area pacing remain demanding …

ventricular dyssynchrony
cardiac resynchronization therapy
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  • 19 Feb, 2024
Skin-to-skin Contact in Neonatal Intensive Care Unit (NICU) Caregiving Touch and Neural Correlates of Slow Stroking Touch in Preterm Infants

Preterm (PT) infants spend their first weeks of life in Neonatal Intensive Care Unit (NICU) where receive little affective physical contact, which plays a crucial role in brain development. Evidence indicates that skin-to-skin contact (SSC) has a positive effect on infants' neurophysiological and behavioral adjustment to postnatal life. Moreover, caregiving …

social interaction
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  • 19 Feb, 2024