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Found 1041 clinical trials
Internet Intervention for Diabetes Distress.

Diabetes distress is a psychological phenomenon associated with the self-management of the disease and is characterized by feelings of anxiety, guilt, helplessness, defeat, and depression. Research suggests that internet-delivered interventions have the potential to increase people's ability to self-manage their symptoms, but whether they are effective is largely unknown. This …

Accepts healthy volunteers
  • 0 views
  • 20 Jun, 2025
  • 19 locations
Part II: Granulocyte-Colony Stimulating Factor Adjunct Therapy for Biliary Atresia

The Investigators propose to test the hypothesis that GCSF enhances the clinical outcome of biliary atresia in a multi-institutional Phase 2 trial to prospectively evaluate the safety and efficacy of GCSF in each of the 2 groups of newly diagnosed BA patients: KBA (i.e., Kasai-operated) or NoK (i.e., patients who …

cholangiography
g-csf
gcsf
colony stimulating factor
direct bilirubin
  • 0 views
  • 19 Feb, 2024
Non Fusion Surgery in Adolescent Idiopathic Scoliosis Patients

The primary objective of the study is to monitor the effectiveness of a minimal invasive non-fusion double rod bipolar posterior spinal implant (Nemost growing domino) to correct the scoliotic curve in growing patients suffering from progressive adolescent idiopathic scoliosis (AIS) who have failed conservative treatment.

spine surgery
scoliosis
conservative therapy
x-rays
  • 0 views
  • 19 Feb, 2024
Selective Caries vs Stepwise Caries Removal Technique in Deep Carious Lesions

The aim of this clinical study is to compare and evaluate the Success of Selective Caries vs Stepwise Caries Removal Techniques in treatment of dental caries.

dental caries
deep caries
caries removal
cold
  • 0 views
  • 19 Feb, 2024
Exercise and Tumor Blood Flow in Breast Cancer Patients

This research aims at investigating tumor blood flow response to acute exercise in human cancer patients. It is hypothesized and expected that acute exercise increases tumor blood flow, which could plausibly increase the efficacy of cancer treatment.

cancer treatment
  • 0 views
  • 19 Feb, 2024
Anti-GITR/Anti-PD1/Stereotactic Radiosurgery in Recurrent Glioblastoma

This is a phase II study of the combination of the GITR agonist monoclonal antibody INCAGN01876, the anti-PD1 monoclonal antibody INCMGA00012, and stereotactic radiosurgery (SRS) for recurrent Glioblastoma (GBM). The investigators hypothesize that the proposed regimen will be safe and stimulate a robust anti-tumor immune response and result in improved …

vasectomy
radiation necrosis
monoclonal antibodies
PCR test
absolute lymphocyte count
  • 0 views
  • 19 Feb, 2024
Safety of Manganese Restriction in Neonatal Parenteral Nutrition

Participants will be <= 32 weeks gestational age (GA) neonates randomized to parenteral nutrition (PN) prepared with standard dose trace elements or to PN prepared with standard trace elements minus manganese.

  • 0 views
  • 19 Feb, 2024
Treatment of Refractory Diamond-Blackfan Anemia With Eltrombopag

Background Diamond-Blackfan anemia (DBA) is treated with steroids. But some people cannot take steroids, or steroids don t work. Other patients must get blood transfusions regularly which are time consuming and can have significant side effects. The drug eltrombopag can increase red blood cells. Researchers want to see if it …

bone marrow biopsy
anemia
cell counts
electrocardiogram
corticosteroids
  • 0 views
  • 19 Feb, 2024
Safety Tolerability and Pharmacokinetics of ARCT-810 in Healthy Adult Subjects

Determine the safety, tolerability and pharmacokinetics of single doses of ARCT-810 in healthy adult subjects.

  • 0 views
  • 19 Feb, 2024
Deep Anterior Lamellar Keratoplasty Using Dehydrated Versus Standard Organ Culture Stored Donor Corneas

The objective of this study is to assess the outcomes between deep anterior lamellar keratoplasty using dehydrated versus standard organ culture stored donor corneas.

lamellar keratoplasty
corneal transplant
keratoconus
  • 0 views
  • 19 Feb, 2024