Found 2,824 clinical trials

E EAS FHSC Coordinating Centre

EAS Familial Hypercholesterolaemia Studies Collaboration

Familial hypercholesterolaemia (FH) is a common genetic disorder resulting in marked elevations in low-density lipoprotein cholesterol (LDL-C). If untreated, lifelong exposure to elevated LDL-C results in a substantially increased risk of (premature) cardiovascular disease as compared to the general population. Although FH adverse cardiovascular outcomes are potentially preventable through early …

100 years and younger All Phase N/A

B Branda Mallon

Pediatric Hepatic Tumors

Centralized biological collection of multicentric origin, retrospective and prospective of biological samples (tissues and fluids) taken within the framework of the diagnostic and therapeutic management of children and adolescents with liver tumor, and supported in the centers of French Society for Childhood Cancers (SFCE) with associated clinical database.

18 years and younger All Phase N/A

Y Yang Jin

Study for Novel Coronavirus Pneumonia (NCP)

To develop practical and effective clinical diagnosis and treatment schemes for the control of novel coronavirus pneumonia.

18-90 years All Phase N/A

P Philipp Latzin, MD PhD

Early Environmental and Maternal Determinants of Airway Inflammation in Wheezing Disorders in Infants

This study collects data on microbiological, genetic and environmental factors, as well as lung function parameters (e.g. spirometry, body plethysmography, lung-MRI) to assess the complex interaction of predisposing risk factors for impaired lung development and respiratory diseases.

100 years and younger All Phase N/A

R Rachel Kronman-Gross, BS

DeBakey Cardiovascular Magnetic Resonance Study

While advancements in cardiac magnetic resonance (CMR) have improved image quality, it is unclear how these improvements are connected to the clinical evaluation of individuals with cardiovascular disease. The aim of this large prospective registry revolves around 4 key principles: 1) utilize CMR to gain additional pathophysiologic insights into cardiovascular …

100 years and younger All Phase N/A

A Assami Rösner, PhD

Prediction of Outcome by Echocardiography in Left Bundle Branch Block

Patients with left bundle branch block have an increased risk for the development of heart-failure and death. However, risk factors for unfavorable outcomes are still poorly defined. This study aims to identify echocardiographic parameters and ECG characteristics by machine learning in order to develop individual risk assessment

18 years and older All Phase N/A

S Sofia Bergenstråle

A 48-Month Study to Evaluate Long-Term Effectiveness of Elocta on Joint Health

This is a 48-month observational, prospective, multicentre study. The overall aim of the study is to evaluate the long-term effectiveness of Elocta treatment on joint health in patients treated prophylactically with Elocta in a real-world setting.

100 years and younger All Phase N/A

F Francesco Panzuto

Database ITANET - ENETS Registry

This is a prospective observational study with the aim to create an Italian database for the collection of data on diagnostic approach, therapy and follow up of patients affected by GEP-NET (gastro-enteric-pancreatic neuroendocrine tumours) and to include these data into a multi-national European registry database, adhering to the ENETS (european …

19 years and older All Phase N/A

S Susanna Del Signore, M.D.

Geriatric Population COVID-19 Observational Study (GEROCOVIDobs)

The GeroCovid e-Registry is a European de-identified clinical data electronic registry of geriatric patients at risk or suffering from COVID-19 (suspected and confirmed cases) observed since 1st March 2020 in the participating investigational sites.

60 years and older All Phase N/A

A Alicia Gainza Calleja, BN

EP Device Registry

This study will provide ongoing, high quality data on the safety, performance, and clinical benefits of Abbott's EP devices in a real-world setting.

100 years and younger All Phase N/A