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Found 194 clinical trials
A Study of BPI-1178 in Patients With Advanced Solid Tumor and HR+/HER2- Breast Cancer

BPI-1178 is a novel, orally administered inhibitor of both cyclin-dependent kinase 4CDK4and CDK6 kinase activity. The purpose of this study is to evaluate the safety, efficacy and pharmacokinetics of BPI-1178 in subjects with advanced solid tumor, as well as the subjects with advanced hormone receptor-positive(HR+)/human epidermal growth factor receptor 2 …

stage iv breast cancer
advanced malignant solid tumor
epidermal growth factor receptor
fulvestrant
absolute neutrophil count
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  • 19 Feb, 2024
  • 1 location
The Use of Indocyanine Green as a Diagnostic Adjunct for Pediatric Solid Malignancies

Use of indocyanine green will augment the accuracy of identification and resection of both primary solid malignancies as well as their pulmonary metastases, where applicable We will conduct a prospective feasibility study of pediatric patients with solid malignancies with or without lung metastatases who present at the time of initial …

pulmonary metastasis
metastatic malignancy
metastasis
cancer
ct scan
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  • 19 Feb, 2024
  • 1 location
Optimizing Y90 Therapy for Radiation Lobectomy

HCC resection candidates with inadequate future liver remnant will be enrolled in this study. They will be treated with Y90 radioembolization to help grow the liver enough to undergo liver resection. There will be 2 Patient Groups. The first group of patients will be treated with Y90 dose and embolic …

liver disease
cirrhosis
hepatectomy
liver diseases
radioembolization
  • 0 views
  • 19 Feb, 2024
  • 1 location
The Role of Micrometastasis and Isolated Tumor Cells (ITCs) in Endometrial and Cervical Cancer. A Multicenter Study.

The role of small-volume lymph node disease (ITC and micro metastases) among patients with endometrial or cervical cancer submitted to sentinel node (SLN) procedure is not clearly defined. This study was designed to create a dataset of patients with lymph nodal disease. Data on type and volume of lymph nodal …

nucleic acid amplification
sentinel node
endometrial cancer
cervical cancer
cancer
  • 0 views
  • 19 Feb, 2024
  • 1 location