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Found 13 clinical trials
IVIG With Rituximab vs Rituximab as First Line Treatment of Pemphigus

However; the prolonged use of high dose steroids carries significant side effects. A recent randomized trial has proved the efficacy of Rituximab, a monoclonal anti-CD20 antibody against B-lymphocytes, as an efficacious therapy for pemphigus. Early use of rituximab was associated with better clinical outcomes, hence combination treatment of rituximab and …

enzyme-linked immunosorbent assay
acantholysis
anti-cd20 antibody
elisa
immunosuppressive agents
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  • 19 Feb, 2024
VR-CAP in the First-line Treatment for Patients With Marginal Zone Lymphoma

This is a prospective single arm, multi-center, phase II clinical trial to observe the efficacy and safety of VR-CAP (Velcade and Rituximab-Cyclophosphamide, Epirubicin and Prednisone) in the first-line treatment for patients with marginal zone lymphoma.

cyclophosphamide
lymphoma
marginal zone lymphoma
prednisone
epirubicin
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  • 19 Feb, 2024
FT596 as a Monotherapy and in Combination With Anti-CD20 Monoclonal Antibodies

This is a Phase I dose-finding study of FT596 as monotherapy and in combination with Rituximab or Obinutuzumab in subjects with relapsed/refractory B-cell Lymphoma or Chronic Lymphocytic Leukemia. The study will consist of a dose-escalation stage and an expansion stage where participants will be enrolled into indication-specific cohorts.

contraceptive use
leukemia
rituximab fludarabine
lymphoma
refractory b-cell non-hodgkin lymphoma
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  • 19 Feb, 2024