epidermal growth factor Clinical Research Trials

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Found 13 clinical trials

Multi-country trial
Phase 1
For Seniors
For adults
Recruiting in 10s
Interventional Study
For Females
Family Medicine
Recruiting

A Study of H3B-6545 in Combination With Palbociclib in Women With Advanced or Metastatic Estrogen Receptor-Positive Human Epidermal Growth Factor Receptor-2 (HER2)-Negative Breast Cancer

The primary objective of this study is to evaluate the safety and tolerability of H3B-6545 and palbociclib when administered in combination in order to determine the maximum tolerated dose (MTD) and/or the recommended Phase 2 dose (RP2D) of this combination in women with advanced or metastatic estrogen receptor-positive (ER+) HER2- …

her2- breast cancer

HER2

estrogen receptor

stage iv breast cancer

cancer

0 views
19 Feb, 2024

Phase 2
For Seniors
For adults
Recruiting in 100s
Interventional Study
all
Family Medicine
Recruiting

Concurrent Chemoradiotherapy With Nimotuzumab for High Risk Nasopharyngeal Carcinoma

This is the first phase II randomized clinical trial of concurrent chemoradiotherapy with or without EGFR blocker Nimotuzumab for high risk advanced nasopharyngeal carcinoma(NPC) , determining whether concurrent chemoradiotherapy(CCRT) combined with nimotuzumab can improve the survival rate of high-risk patients and may provide new evidence for individualized comprehensive treatment of …

induction chemotherapy

epstein-barr virus dna

carcinoma

cancer

nasopharyngeal carcinoma

4 views
19 Feb, 2024

Phase 3
For Seniors
For adults
Recruiting in 100s
Interventional Study
all
Family Medicine
Recruiting

Radiotherapy Plus Nimotuzumab or Cisplatin in Nasopharyngeal Carcinoma

This is a phase III randomized clinical trial of definitive radiotherapy plus EGFR blocker nimotuzumab versus radiotherapy plus cisplatin(CCRT) for nasopharyngeal carcinoma (NPC) patients with favorable response to induction chemotheray(IC), determining whether radiotherapy combined with nimotuzumab was non-inferior to CCRT and may provide new evidence for individualized comprehensive treatment of …

induction chemotherapy

epstein-barr virus dna

carcinoma

cancer

EGFR

0 views
19 Feb, 2024