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Found 109 clinical trials
Age-Related Macular Degeneration Benchmark Imaging Dataset (ABID)

1000 participants from up to 25 international locations who are at least 50 years old with either healthy eyes or a diagnosis of Age-Related Macular Degeneration (AMD) will be consented to provide images of their eyes for a new dataset. This dataset is an important step in developing an Artificial …

Accepts healthy volunteers
  • 0 views
  • 19 May, 2025
Assessment of the Efficacy Safety and Tolerability of AVP-786 for the Treatment of Agitation in Patients With Dementia of the Alzheimer's Type

This study will be conducted to evaluate the efficacy, safety, and tolerability of AVP-786 (deudextromethorphan hydrobromide [d6-DM]/quinidine sulfate [Q]) compared to placebo for the treatment of agitation in participants with dementia of the Alzheimer's type.

  • 0 views
  • 19 Feb, 2024
A Study of CAD106 and CNP520 Versus Placebo in Participants at Risk for the Onset of Clinical Symptoms of Alzheimer's Disease

The purpose of this study is to test whether two investigational drugs called CAD106 and CNP520, administered separately, can slow down the onset and progression of clinical symptoms associated with Alzheimer's disease (AD) in participants at the risk to develop clinical symptoms based on their age and genotype.

mental state examination
apolipoprotein e4
Accepts healthy volunteers
mini-mental state examination
alzheimer's disease
  • 32 views
  • 20 Sep, 2024
  • 127 locations
A Multinational Randomized Double-blind Placebo-controlled Study to Assess the Efficacy Pharmacodynamics Pharmacokinetics and Safety of Venglustat in Late-onset GM2

Primary Objectives: Primary population (adult participants with late-onset GM2 gangliosidosis): To assess the efficacy and pharmacodynamics (PD) of daily oral dosing of venglustat when administered over a 104-week period Secondary population (participants with juvenile/adolescent late-onset GM2 gangliosidosis, GM1 gangliosidosis, saposin C deficiency, sialidosis type 1 or juvenile/adult galactosialidosis): To assess …

  • 0 views
  • 19 Feb, 2024
  • 2 locations
Mobility Protocol Adapted for Advanced Visually Impaired Subjects

Retinitis Pigmentosa is characterized by a progressive disappearance of photoreceptors, responsible for a progressive and severe loss of vision. People Retinitis Pigmentosa therefore encounter a large number of difficulties in daily life, specifically for: Visual research Visuo-motor coordination in tasks requiring fine motor control Visuo-motor coordination in mobility tasks This …

cognitive disorders
amblyopia
low vision
visual impairment
retinitis
  • 0 views
  • 19 Feb, 2024
Trial With the Treatment of Sertraline in Youth With Generalized Separation and/or Social Anxiety Disorders.

A Multicenter, acute, randomized, double-blind, placebo-controlled, flexible-dose trial with the treatment of sertraline.

separation
mania
estrogen
urine drug screen
anxiety
  • 0 views
  • 19 Feb, 2024
Phase 2 Study to Evaluate the Efficacy and Safety of Irbesartan and Amlodipine Combined or Alone in Patients With Essential Hypetension

A Randomized, Double-blind, Multicenter, Factorial Design, Phase II Study to Evaluate the Efficacy and Safety of Irbesartan and Amlodipine Combined or Alone in Patients With Essential Hypertension

irbesartan
essential hypertension
hypertension
amlodipine
  • 0 views
  • 19 Feb, 2024
Effects and Safety of Epidural PDRN vs. Placebo

This is a single-center, randomized, double-blind clinical study to assess the clinical application and outcomes with epidural PDRN versus Normal saline injection in patients with spinal stenosis.

normal saline
spinal stenosis
stenosis
intermittent claudication
  • 0 views
  • 19 Feb, 2024
The Efficacy and Safety of Pyramax in Mild to Moderate COVID-19 Patients

This study is a multi-center, randomized, double-blind, parallel, placebo-controlled, phase clinical trial to evaluate efficacy and safety of Pyramax in mild to moderate COVID-19 patients.

oropharyngeal
covid-19
SARS
oximetry
acute respiratory syndrome (sars)
  • 0 views
  • 19 Feb, 2024
Efficacy of Ivermectin in Adult Patients With Early Stages of COVID-19

Double blind, placebo controlled, randomized clinical trial to evaluate the efficacy of ivermectin in preventing progression of disease in adult patients with early stages of COVID-19

SARS
covid-19
ivermectin
acute respiratory syndrome (sars)
  • 0 views
  • 19 Feb, 2024