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Found 108 clinical trials
A Study of CAD106 and CNP520 Versus Placebo in Participants at Risk for the Onset of Clinical Symptoms of Alzheimer's Disease

The purpose of this study is to test whether two investigational drugs called CAD106 and CNP520, administered separately, can slow down the onset and progression of clinical symptoms associated with Alzheimer's disease (AD) in participants at the risk to develop clinical symptoms based on their age and genotype.

apolipoprotein e4
mini-mental state examination
mental state examination
alzheimer's disease
Accepts healthy volunteers
  • 32 views
  • 20 Sep, 2024
  • 127 locations
A Multinational Randomized Double-blind Placebo-controlled Study to Assess the Efficacy Pharmacodynamics Pharmacokinetics and Safety of Venglustat in Late-onset GM2

Primary Objectives: Primary population (adult participants with late-onset GM2 gangliosidosis): To assess the efficacy and pharmacodynamics (PD) of daily oral dosing of venglustat when administered over a 104-week period Secondary population (participants with juvenile/adolescent late-onset GM2 gangliosidosis, GM1 gangliosidosis, saposin C deficiency, sialidosis type 1 or juvenile/adult galactosialidosis): To assess …

  • 0 views
  • 19 Feb, 2024
  • 2 locations
Mobility Protocol Adapted for Advanced Visually Impaired Subjects

Retinitis Pigmentosa is characterized by a progressive disappearance of photoreceptors, responsible for a progressive and severe loss of vision. People Retinitis Pigmentosa therefore encounter a large number of difficulties in daily life, specifically for: Visual research Visuo-motor coordination in tasks requiring fine motor control Visuo-motor coordination in mobility tasks This …

cognitive disorders
retinitis
visual impairment
low vision
amblyopia
  • 0 views
  • 19 Feb, 2024
Trial With the Treatment of Sertraline in Youth With Generalized Separation and/or Social Anxiety Disorders.

A Multicenter, acute, randomized, double-blind, placebo-controlled, flexible-dose trial with the treatment of sertraline.

adjustment disorder
psychosis
social phobia
progestin
evra
  • 0 views
  • 19 Feb, 2024
Phase 2 Study to Evaluate the Efficacy and Safety of Irbesartan and Amlodipine Combined or Alone in Patients With Essential Hypetension

A Randomized, Double-blind, Multicenter, Factorial Design, Phase II Study to Evaluate the Efficacy and Safety of Irbesartan and Amlodipine Combined or Alone in Patients With Essential Hypertension

irbesartan
amlodipine
hypertension
essential hypertension
  • 0 views
  • 19 Feb, 2024
Effects and Safety of Epidural PDRN vs. Placebo

This is a single-center, randomized, double-blind clinical study to assess the clinical application and outcomes with epidural PDRN versus Normal saline injection in patients with spinal stenosis.

spinal stenosis
intermittent claudication
normal saline
stenosis
  • 0 views
  • 19 Feb, 2024
The Efficacy and Safety of Pyramax in Mild to Moderate COVID-19 Patients

This study is a multi-center, randomized, double-blind, parallel, placebo-controlled, phase clinical trial to evaluate efficacy and safety of Pyramax in mild to moderate COVID-19 patients.

SARS
oropharyngeal
acute respiratory syndrome (sars)
covid-19
oximetry
  • 0 views
  • 19 Feb, 2024
Efficacy of Ivermectin in Adult Patients With Early Stages of COVID-19

Double blind, placebo controlled, randomized clinical trial to evaluate the efficacy of ivermectin in preventing progression of disease in adult patients with early stages of COVID-19

acute respiratory syndrome (sars)
SARS
covid-19
ivermectin
  • 0 views
  • 19 Feb, 2024
Waking Hypnosis in the Treatment of MS-related Fatigue

The proposed study is a single-center, single-blind three-group randomized (1:1:1) controlled trial (RCT) comparing two hypnosis interventions to waitlist control efficacy for MS-related fatigue.

fatigue
  • 0 views
  • 19 Feb, 2024
Evaluate the Safety and Efficacy of Botulax in Subjects With Benign Masseteric Hypertrophy

This study is A Randomized, Double-blind, Placebo-controlled, Multi-center Phase II Optimal Dose-finding Study to Evaluate the Safety and Efficacy of Botulax in Subjects with Benign Masseteric Hypertrophy

  • 0 views
  • 19 Feb, 2024