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Found 15 clinical trials
Sample Collection for Systems Evaluation of Patients With Unknown or Incompletely Characterized Immune Defects

Background The immune system defends the body against disease. It has many different parts spread out in the body, including in the blood and skin. To learn more about it, researchers want to study samples from people with healthy immune systems and people with conditions that affect how the immune …

gastrointestinal symptoms
autoimmune disease
dermatitis
endoscopies
episodic fever
  • 0 views
  • 19 Feb, 2024
MPA AUC Monitoring in Patients Receiving MMF for Diffuse Cutaneous or Pulmonary Involvement in Systemic Sclerosis

To define a target value of AUC MPA to improve the modified Rodnan score and / or respiratory impairment (DLCO or FVC) at one year in patients receiving MMF for the treatment of diffuse cutaneous or interstitial lung damage of systemic sclerosis.

progressive systemic sclerosis
pulmonary involvement
skin sclerosis
sclerosis skin
chest ct
  • 0 views
  • 19 Feb, 2024
Study of the Thyroid Function and Echostructural Morphology in Patients Affected With Rasopathies (ECORAS2023) (ECORAS2023)

The study aims to evaluate the prevalence of thyroid disease, particularly with autoimmune pathogenesis (isolated hyperthyrotropinemia, hyperthyroidism, hypothyroidism, thyroid nodules) and/or morphostructural abnormalities of the thyroid gland in patients with RASopathy genetically confirmed by NGS technique (analysis of the genes: BRAF, CBL, HRAS, KRAS, LZTR1, MAP2K1, MAP2K2, MRAS, NRAS, PPP1CB, …

Accepts healthy volunteers
  • 0 views
  • 30 Jul, 2024
Th1/Th2/Th17/TREG and TLRs Activation/KIR for COVID 19 Prediction of Outcome

To ascertain globally the changes in the cytokines involved and TLRs/KIR activation in patients admitted to the hospital with a COVID-19 diagnosis, and the changes after initiation of the different therapies

covid-19
cytokines
  • 0 views
  • 19 Feb, 2024
Biomarkers in Polyradiculoneuropathies

The nodes of Ranvier contain ion channels that enable the rapid propagation of the nerve impulse. Cell adhesion molecules and glycolipids play an important role in the formation of the nodes of Ranvier. Antibodies against glycolipids are detected in half of patients with Guillain-Barr syndrome, an acute inflammatory neuropathy affecting …

fibres
neuromuscular diseases
neuropathy
ion channels
inflammatory neuropathy
  • 0 views
  • 19 Feb, 2024