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Found 194 clinical trials
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Modality of Adjuvant Radiotherapy and Chemotherapy for Stage Endometrial Cancer

There is a consensus that adjuvant radiochemotherapy is needed for stage endometrial cancer, but the best modality of radiochemotherapy is still uncertain. The retrospective data of our center showed that the sequential radiochemotherapy of "chemotherapy-radiotherapy-chemotherapy" in the "sanwich" mode could improve the survival outcome in patients with advanced endometrial cancer.

adjuvant
neutrophil count
chemoradiotherapy
endometrial adenocarcinoma
carcinoma
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  • 19 Feb, 2024
  • 1 location
Sentinel Lymph Node Sampling for Patients With Middle-high Risk Endometrial Cancer Confined to the Uterus

Aim To investigate the effect of sentinel lymph node (SLN) sampling on the prognosis of patients with middle-high risk endometrial cancer obviously confined to the uterus before surgery.

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  • 19 Feb, 2024
  • 1 location
Durvalumab With or Without Olaparib as Maintenance Therapy After First-Line Treatment of Advanced and Recurrent Endometrial Cancer

A study to assess the efficacy and safety of durvalumab in combination with platinum-based chemotherapy (paclitaxel + carboplatin) followed by maintenance durvalumab with or without olaparib for patients with newly diagnosed advanced or recurrent endometrial cancer.

measurable disease
adjuvant
maintenance therapy
immunomodulator
platinum-based chemotherapy
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  • 19 Feb, 2024
  • 95 locations
A Study of Sacituzumab Govitecan (IMMU-132) in Endometrial Carcinoma

This is a non-randomized Phase 2 study of sacituzumab govitecan (IMMU-132) in subjects with persistent or recurrent endometrial carcinoma.

measurable disease
formalin-fixed paraffin-embedded
major surgery
ct scan
metastasis
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  • 19 Feb, 2024
  • 1 location
De-escalated Conformal Radiation Expedited Sequentially With Chemotherapy for Endometrial Cancer

The goal of this study is to evaluate short course radiation in the post-operative female pelvis after hysterectomy in stage III-IVA endometrial adenocarcinoma patients, or any stage patients with uterine serous or carcinosarcoma histology. The investigators hypothesize that short course pelvic radiation will have an acute and late grade 3-4 …

neutrophil count
endometrial adenocarcinoma
carcinosarcoma
hysterectomy
adenocarcinoma
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  • 19 Feb, 2024
  • 1 location
The Application of Real-Time Near-infrared Imaging in Gynecological Surgery

Removing in situ and metastasis lesions completely during gynecological surgery is central to reduce the recurrence and death, and the identification of lesions in traditional gynecological surgery often depends on the experience of surgeons. The identification of nerves is often needed in gynecological surgery, such as the obturator nerves in …

iia2
pelvic lymphadenectomy
uterine sarcoma
gynecologic surgery
ovarian cancer
  • 0 views
  • 19 Feb, 2024
  • 1 location