advanced malignant solid tumor Clinical Research Trials

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Found 183 clinical trials

Phase 1
For Seniors
For adults
Recruiting in 100s
Interventional Study
all
Cardiovascular Diseases
Recruiting

NBE-002 in Patients With Advanced Solid Tumors

This first-in-human study will evaluate the recommended dose for further clinical development, safety, tolerability, anti-tumor activity, immunogenicity, pharmacokinetics and pharmacodynamics of NBE-002, a novel anti-ROR1 antibody-drug conjugate, in patients with advanced solid tumors.

solid neoplasm

advanced solid tumor

progressive disease

measurable disease

cancer

0 views
19 Feb, 2024
2 locations

Phase 1
For Seniors
For adults
Recruiting in 100s
Interventional Study
all
Family Medicine
Recruiting

Brief Title: Study of BGB-10188 as Monotherapy and in Combination With Zanubrutinib and Tislelizumab

The purpose of this study is to determine the maximum tolerated dose (MTD), recommended Phase 2 dose(RP2D),safety & tolerability of BGB-10188: as monotherapy in participants with mature B-cell malignancies; oin combination with zanubrutinib in participants with relapse/refractory follicular lymphoma (R/R FL), mantle cell lymphoma (MCL) or diffuse large B-cell lymphoma …

cancer, ovarian

b-cell lymphoma

solid tumors

small cell lung cancer

cancer

0 views
19 Feb, 2024
4 locations

For Seniors
For adults
Recruiting in 10s
Observational Study
all
Recruiting

L-TIL in Patients With Malignancy Resistance to Anti-PD-1 Therapy

Safety and effectiveness of liquid tumor infiltrating lymphocytes in patients with advanced malignant tumors who have failed to anti-PD-1 therapy

blood pregnancy test

cancer

measurable disease

0 views
19 Feb, 2024
1 location