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Found 2,825 clinical trials

D Dulce González-Islas, PhD

Effect of Nutritional Supplementation and Pulmonary Rehabilitation on the Clinical Status of HF and COPD

Cardiovascular diseases (CVD) are the leading cause of death in the world and our country. The prevalence of Heart Failure (HF) is 1-2% in the adult population in developed countries, up to 10% among people 70 years of age. Concerning COPD, it is estimated that by 2030 will be the …

40 years and older All Phase N/A
U UCB Cares

A Study to Evaluate Safety Tolerability Pharmacokinetics and Pharmacodynamics of UCB8600 in Healthy Participants Atopic Participants and Chronic Spontaneous Urticaria Participants

The purpose of the study is to assess safety, tolerability and pharmacokinetics (PK) of oral UCB8600.

18-65 years All Phase 1
C Carina F Salgueiro, MSc

Mobile App as a Guide to Exercises for Patients With Chronic Stroke

Introduction: Stroke continues to be one of the leading causes of disability in the Spanish adult population with the presentation of impairments such as alteration of mobility and a consequent reduction in quality of life. These sequelae, generally chronic, generates a significant expense and saturation of social and health services. …

18 years and older All Phase N/A
E Ekaterina A Kosovskikh

The Study of Biological Prosthetic Heart Valves With the "Easy Change" System

The study of new biological heart valves with the "easy change" system, including an assessment of the basic hemodynamic characteristics of the prosthesis, complications associated with valve implantation, and general mortality

60 years and older All Phase N/A
J Jessica Yang, MBBS

HCC Surveillance: Comparison of Abbreviated Non-contrast MRI and Ultrasound Surveillance in Cirrhotic Patients With Suboptimal Ultrasound Visualisation

All international guidelines recommend 6-monthly ultrasound surveillance for patients at risk for liver cancer (hepatocellular carcinoma or HCC), such as patients with cirrhosis. The aim of surveillance is to detect HCC at an early stage when it is still potentially curable. Currently only 4 out of 10 HCCs are detected …

20-85 years All Phase N/A
A Andrey A Karpenko, PHD

Full Metall Jacket Multilevel Segment

Hypothesis: "Total" endovascular revascularization of a multistory lesion of the iliac-femoral-popliteal segment is safer and a better quality of life is achieved in comparison with hybrid intervention. The lack of damage to the skin avoids complications in the postoperative and remote periods of observation, thereby improving the quality of life

45-80 years All Phase N/A
A Alan L Ho, MD, PhD

Vemurafenib Plus Copanlisib in Radioiodine-Refractory (RAIR) Thyroid Cancers

The purpose of this study is to develop a new drug treatment to reverse tumor resistance to radioiodine in BRAF mutant tumors so that radioiodine can be given to shrink tumors. This study is also being done to find out the highest doses of copanlisib and vemurafenib that, when given …

18 years and older All Phase 1
K Korgün Ökmen, Assoc.Phd.M.D.

The Effect of Regional Anesthesia Techniques on Brain Tissue Oxygenation in Thoracic Surgery

Today, it is preferred that the lung with pathology for thorax surgery is not under ventilation during operation in terms of reliability and ease of operation. For this reason, the anesthesia approach is characteristic and it is ensured that the single lung is not ventilated during the operation by means …

18-65 years All Phase N/A
S Sohaib Ashraf, MBBS

Efficacy of Subcutaneous Ivermectin With or Without Zinc and Nigella Sativa in COVID-19 Patients

To measure the effect of Ivermectin (sub-cutaneous) with or without zinc and Nigella sativa in treating the COVID-19 patients to clear viral load of SARS-CoV-2 along with reduction in severity of symptoms and length of hospitalization of patients with COVID-19.

18 years and older All Phase 1/2
D David D'Alessandro, MD

Preoperative Percutaneous RVAD to Preemptively Treat Right Heart Failure Post-LVAD

Prior studies have shown that left ventricular assist device (LVAD) implantation commonly results in right ventricular failure (RVF). Right ventricular dysfunction and failure after LVAD implantation is known to increase morbidity and mortality and contribute to longer post-implant hospital length of stay. Since RVF is difficult to predict and can …

18-75 years All Phase N/A

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