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Found 175 clinical trials
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Neoadjuvant T-VEC in High Risk Early Melanoma

Despite the recent notable advances in the treatment of advanced melanoma with application of growing immunotherapies, patterns of response and factors resulting in treatment failure are poorly understood. Moreover, the application of these therapeutics has been limited in the neoadjuvant setting, particularly in earlier stage disease, even though this strategy …

cancer
primary tumor
immunotherapies
karnofsky performance status
melanoma stage
  • 0 views
  • 19 Feb, 2024
  • 1 location
Dose Escalation of DF6002 in Patients With Advanced Solid Tumors and Expansion in Selected Indications

This study is a Phase 1/2, open-label, dose-escalation study with a consecutive parallel-group efficacy expansion study, designed to determine the safety, tolerability, PK, pharmacodynamics, and preliminary anti-tumor activity of DF6002 as monotherapy and in combination with pembrolizumab.

solid neoplasm
programmed cell death 1 ligand 1
neuropathy
advanced urothelial carcinoma
cancer
  • 0 views
  • 19 Feb, 2024
  • 1 location