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Found 1697 clinical trials
Molecular Characteristics of Gastroesophageal Adenocarcinoma (MOCHA): A Prospective Feasibility Study

Researchers are looking to further our knowledge on disease biology and treatment selection for gastroesophageal adenocarcinoma. The purpose of this study is to see how useful it is to look for changes and characteristics in your genes (molecules that contain instructions for the development and functioning of the cells) and …

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  • 19 Feb, 2024
CT-guided Stereotactic Body Radiation Therapy and MRI-guided Stereotactic Body Radiation Therapy for Prostate Cancer MIRAGE Study

This phase III trial studies compares CT-guided stereotactic body radiation therapy and MRI-guided stereotactic body radiation therapy (SBRT) in treating prostate cancer. Image-guided SBRT is a standard treatment for prostate cancer, which combines imaging of the cancer within the body with the delivery of therapeutic radiation doses produced on a …

positron emission tomography
adenocarcinoma of prostate
axumin
stereotactic body radiation therapy
prostate cancer
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  • 19 Feb, 2024
Evaluation of Clinical Radiomics and Molecular Features of Lung Metastasis in PDAC Patients (LUMACA Trial)

The aim of this study is the characterization from epidemiological, radiomics and molecular point of view of lung metastasis of patients at beginning affected by pancreatic adenocarcinoma (PDAC), which after the resection of primitive tumor have met with initial recurrence of the disease exclusively at the lung level.

adenocarcinoma
primary tumor
pdac
pancreatic adenocarcinoma
metastasis
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  • 19 Feb, 2024
Frailty in Elderly Patients With COVID-19

This is a monocentric retro-prospective observational study that wants to evaluate the relation between frailty and clinical outcomes in elderly patients with COVID-19.

pneumonia
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  • 19 Feb, 2024
Integrative Therapy for Holistic Natural Cognition and Lifestyle Rehabilitation

An observational study to determine outcomes of older adults who are under naturopathic medical care for cognitive complaints at a specific clinic in Southern California.

cognitive assessment
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  • 19 Feb, 2024
Complex Decongestive Therapy on Distal Radius Fracture

Trauma results in inflammatory reactions accompanied by high protein edema. Trauma can also reduce the carrying capacity of the lymphatic system below normal lymphatic load, leading to exposure of lymphedema. Cellular wastes accumulated in interstitial fields and prolonged exudation period create a physiological problem. It causes the recovery time of …

distal radius fracture
complex decongestive therapy
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  • 19 Feb, 2024
L-TIL in Patients With Malignancy Resistance to Anti-PD-1 Therapy

Safety and effectiveness of liquid tumor infiltrating lymphocytes in patients with advanced malignant tumors who have failed to anti-PD-1 therapy

measurable disease
cancer
blood pregnancy test
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  • 19 Feb, 2024
Predominant Sensitizations to Single Bee Venom Allergens as a Risk Factor for Therapy Failure

Venom immunotherapy (VIT) is an established treatment for Hymenoptera venom allergy and provides long-term protection from further generalized reactions in almost all patients. However, it is still unclear why bee VIT is less effective than vespid VIT. The preliminary data show that not only predominant Api m 10 sensitization but …

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  • 19 Feb, 2024
A Study Using [18F]F AraG PET to Evaluate Response to Checkpoint Inhibitor Therapy(CkIT) in Patients With Solid Tumors

In this study, patients with advanced solid tumors will undergo [18F]F AraG PET/CT imaging to assess for changes in tracer uptake following treatment with CkIT.

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  • 19 Feb, 2024
Biomarkers in Rheumatoid Arthritis Treated With Anti-interleukin-6 Therapy

The use of anti-interleukin (IL)-6 therapy, including tocilizumab, in rheumatoid arthritis or giant cell arteritis, led to the improvement or even control of disease in some patients for whom no further therapeutic options were available. Nevertheless, the evaluation of the efficacy of these treatments are negatively impacted by the lack …

steroidal anti-inflammatory drugs
interleukin
arthritis
tocilizumab
immunosuppressive agents
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  • 19 Feb, 2024