Found 201 clinical trials
LIPAD - LRRK2 International Parkinson's Disease Study
Based on current knowledge, it can be assumed that there are several causes and that the causes may be differ between patients; this makes research into the pathogenesis and possible therapies very difficult. In the case of monogenic Parkinson's diseases, which are due to changes in one gene (e.g. LRRK2), …
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- 19 Feb, 2024
Predictive Factors COVID-19 Patients
This is a monocentric retro-prospective observational study that will be conducted on all COVID19 positive patients hospitalized at the S. Gerardo Hospital in Monza.
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- 19 Feb, 2024
A Study for Post-Marketing Surveillance of Azilsartan Medoxomil in the Treatment of Adult Participants With Essential Hypertension in South Korea
The purpose of this study is to evaluate the safety by determining the incidence rates of all adverse events (AEs) including serious adverse events (SAEs)/serious adverse drug reactions (ADRs), unexpected AEs and ADRs that are not reflected on the precaution in the use, ADRs already known, non-serious ADRs and other …
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- 19 Feb, 2024
A Study for Post-marketing Surveillance of Azilsartan Medoxomil/Chlorthalidone Fixed Dose Combination (FDC) in the Treatment of Participants With Essential Hypertension in South Korea
The purpose of this study is to evaluate the safety by assessing all serious and non-serious adverse events (AEs), irrespective of relatedness or expectedness, as well as other safety parameters including laboratory values, serious adverse events (SAEs)/serious adverse drug reactions (ADRs), unexpected AEs and ADRs that are not reflected on …
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- 19 Feb, 2024
Proton Radiation Therapy Registry
The Johns Hopkins Proton Therapy center is establishing a registry to capture the full 3D radiation dosimetry delivered to the patient, baseline clinical data, and disease, toxicity and quality of life outcomes. The goal is to have all patients treated at the proton center to be included in the registry …
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- 19 Feb, 2024
French Observatory of ElectroConvulsive Therapy (ECT)
Since the 30s, ECT has been a psychiatric treatment mainly used for drug-resistant depressive illnesses. Clinical studies have shown its therapeutic efficiency compared to standard treatments also in other psychiatric illnesses. Although efficient, ECTs also induce side effects. In France, there is currently no consensus on providing the suitest medical …
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- 19 Feb, 2024
Comparative Effectiveness of Targeted Therapy in RA Patients
The objective of a multicenter prospective observational study is to compare effectiveness and safety of biologic disease-modifying antirheumatic drugs and small molecular inhibitors in patients with moderately to severely active rheumatoid arthritis patients who have had an inadequate response or intolerace to methotrexate.
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- 19 Feb, 2024
Using Deep Learning Methods to Analyze Automated Breast Ultrasound Images to Establish a Diagnosis Therapy Assessment and Prognosis Prediction Model of Breast Cancer.
The purpose of this study is using a deep learning method to analyze the automated breast ultrasound (ABUS) imagings, establish and evaluate a diagnosis, therapy assessment and prognosis prediction model of breast cancer. The model would provide important references for further early prevention, early diagnosis and personalized treatment.
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- 19 Feb, 2024
Establishment of Squamous Cell Organoids of the Head and Neck to Assess Their Response to Innovative Therapies
The emergence of tumor organoid cultures in recent years has made it possible to widen the repertoire of available preclinical tumor models and to bridge the gap between cell lines and tumors of xenografted patients in mice (PDXs).These organoids have the advantages of being able to be amplified fairly quickly …
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- 19 Feb, 2024
Blood Biomarker of Alzheimer's Disease (AD)
Currently, no cures or disease modifying therapies exist for Alzheimer's disease (AD). This is partially due to the inability to detect the disease before it has progressed to a stage where there are clinical manifestations.
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- 20 Sep, 2024
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