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Found 1424 clinical trials
Investigating the Effects of Atezolizumab in People Whose Tumour DNA or RNA Indicates Possible Sensitivity

Participants are assigned to one of 8 cohorts based on their primary tumour type: breast, lung, gastrointestinal (GI), primary unknown, genitourinary (GU), sarcoma, gynecological, and 'other' cancer types. Participants in all cohorts will receive the same dose of atezolizumab (1200 mg every 3 weeks).

measurable disease
neutrophil count
atezolizumab
blood transfusion
bone metastases
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  • 19 Feb, 2024
The Application of Real-Time Near-infrared Imaging in Gynecological Surgery

Removing in situ and metastasis lesions completely during gynecological surgery is central to reduce the recurrence and death, and the identification of lesions in traditional gynecological surgery often depends on the experience of surgeons. The identification of nerves is often needed in gynecological surgery, such as the obturator nerves in …

uterine sarcoma
endometriosis
pelvic lymphadenectomy
uterine myomatosis
lymphadenectomy
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  • 19 Feb, 2024
Rigosertib Plus Nivolumab for KRAS+ NSCLC Patients Who Progressed on First-Line Treatment

A Phase1/2a Study of Rigosertib plus Nivolumab in Stage IV Lung Adenocarcinoma Patients with KRAS Mutation who Progressed on First-Line Treatment

drug test
measurable disease
cancer
stage iv lung adenocarcinoma
oophorectomy
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  • 19 Feb, 2024
ABCB1/P-glycoprotein Expression Influence on Non-metastatic Osteosarcoma of the Extremities

Post-authorization, observational, multicenter and prospective study in patients between 2 and 30 years old diagnosed with non-metastatic high-grade osteosarcoma of the extremities. All patients included in the study will receive the initial neoadjuvant treatment prescribed by the doctor of each center, according to standard practice (involving methotrexate, cisplatin, and adriamycin). …

tumor necrosis
localized disease
adjuvant therapy
ifosfamide
glycoprotein
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  • 19 Feb, 2024