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Found 155 clinical trials
A Study to Identify Errors in Inhaler Technique in Adults

This study will observe the inhaler technique of people using 13 different inhaler types; record any technique errors being made against checklists developed for each inhaler device based on their manufacturer's guidelines, and reeducate any observed inhaler technique errors as required.

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  • 19 Feb, 2024
RASopathy Biorepository

The RASopathies are a group of developmental disorders caused by genetic changes in the genes that compose the Ras/mitogen activated protein kinase (MAPK) pathway. New RASopathies are being diagnosed frequently. This pathway is essential in the regulation of the cell cycle and the determination of cell function. Thus, appropriate function …

genetic testing
heart defects
cancer
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  • 19 Feb, 2024
The Real World Study of Neoadjuvant Immunotherapy in Early Stage NSCLC in China

Several published clinical trials have shown the superiority of immunotherapy in neoadjuvant setting. Here we conducted this real world study to see whether neoadjuvant immunotherapy would bring MPR and survival benefits in NSCLC, for example, single agent immunotherapy or immunotherapy combination with chemotherapy. Furthermore biomarker analysis would be also performed …

cancer
measurable disease
EGFR
non-small cell lung cancer
small cell lung cancer
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  • 19 Feb, 2024
Classification of Benign and Malignant Lung Nodules Based on CT Raw Data

The employ of medical images combined with deep neural networks to assist in clinical diagnosis, therapeutic effect, and prognosis prediction is nowadays a hotspot. However, all the existing methods are designed based on the reconstructed medical images rather than the lossless raw data. Considering that medical images are intended for …

cancer
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  • 19 Feb, 2024
Lung Ultrasound in COVID-19 Patients

To assess the prognostic performance of an early global LUS score with respect to the mortality in ICU and duration of ventilation.

lung ultrasound
PCR test
covid-19
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  • 19 Feb, 2024
Immunotherapy in Lung Cancer: Treatment After IO Cessation.

Immunotherapy is now a standard of care for first-line and eventually salvage therapy in patients with stage IV NSCLC and as adjuvant after RT-CT for stage III NSCLC. The aim of the study is determining the therapeutic landscape and the reason for immunotherapy cessation.

cancer
immunomodulators
non-melanoma skin cancer
small cell lung cancer
carcinoma
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  • 19 Feb, 2024
Thromboembolic Events in Severe COVID-19 Patients

The main objective of this study is to describe the incidence of thromboembolic events in a population of patients hospitalized in intensive care units in France for severe COVID-19. The secondary objective of this study is to describe the evolution of hemostasis parameters during the first two weeks of intensive …

covid-19
acute respiratory syndrome (sars)
thromboembolism
haemostasis
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  • 19 Feb, 2024
Sequelae of Sars-CoV-2 Infections

By the end of 2019 a new coronavirus, named SARS-CoV-2, was discovered in patients with pneumonia in Wuhan, China. In the following weeks and months the virus spread globally, having a tremendous impact on global health and economy. To date, no vaccine or therapy is available. Severe courses of the …

cardiovascular system
coronavirus infection
acute respiratory syndrome (sars)
pneumonia
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  • 19 Feb, 2024
Lung Function Exercise Capacity and Health-Related Quality of Life After Severe COVID-19

The medium and long-term impact in survivors of severe COVID-19 on lung function, exercise capacity and health-related quality of life remains to be determined.

fever
coronavirus infection
respiratory tract infection
acute respiratory syndrome (sars)
respiratory distress
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  • 19 Feb, 2024
Evaluation of the Cell Detachment Ratio on pH-responsive Chitosan as a Prognostic Factor in Lung Cancer

The purpose of this project is to evaluate whether the cell detachment ratio on pH-responsive chitosan could be correlated with the overall survival in lung cancer patients. Through controllable cell-material interaction, this project has the intention to develop an alternative tool for both early diagnosis and accurate prognosis in cancer …

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  • 19 Feb, 2024