Found 157 clinical trials
Clinical and Molecular Study of Endometriosis and Adenomyosis
The purpose of this study is to determine whether endometriosis and adenomyosis are progressive diseases, in terms of symptoms (pain, abnormal uterine bleeding and infertility), anatomical lesions size, and recurrences. We also aimed to address molecular questions on immune dialogues between ectopic lesions and the eutopic endometrium, auto-immunity in endometriosis …
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- 19 Feb, 2024
- 1 location
The Multi-Ethnic Lifestyle Study
The study design is cross-sectional using a self-completion questionnaire in an English speaking multi-ethic population within Leicester and Leicestershire. The study will adopt a convenient and purposive sampling recruitment strategy across a variety of settings within Leicestershire to facilitate recruitment of a wide range of participants.
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- 19 Feb, 2024
- 1 location
Complex All-comers and Patients With Diabetes or Prediabetes Treated With Xience Sierra Everolimus-eluting Stents
Drug eluting stents (DES) are widely used for treatment of coronary artery lesions. The Xience Sierra stent has a refined design of the metal stent backbone and is used in patients with various clinical syndromes and in different lesions. Clinical outcome of patients with previously unknown (silent) diabetes and prediabetes …
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- 19 Feb, 2024
- 2 locations
COVID-19 Pandemic Impact on Alcohol (PIA) - A Natural History Study
Surveys will cover the following topics: Alcohol use and its consequences Other substance use Stress Impact of the COVID-19 pandemic Pain Physical health Sleep Quality of life. Because the course of the pandemic may change, the frequency of the surveys may change.
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- 19 Feb, 2024
- 1 location
Pharmacokinetics Pharmacodynamics and Safety Profile of Understudied Drugs Administered to Children Per Standard of Care (POPS)
The study investigators are interested in learning more about how drugs, that are given to children by their health care provider, act in the bodies of children and young adults in hopes to find the most safe and effective dose for children. The primary objective of this study is to …
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- 19 Feb, 2024
- 35 locations
Pulmonary Embolism Prognosis Model
The purpose of this study is to analyze the clinical manifestations, imaging features, and prognosis-related factors of pulmonary embolism, and to explore the prognosis risk assessment model for Chinese patients
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- 19 Feb, 2024
- 1 location
The ATtune Knee Outcome Study
To accomodate dissatisfied patients with a total knee arthroplasty (TKA) and improve outcomes, several knee systems have been developed. The cemented ATTUNE TKA shows superiority over other established knee systems at short-term, abating with longer follow-up. There have been no studies reporting on the results of the uncemented version of …
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- 19 Feb, 2024
- 1 location
Predictors of Better Outcomes After Severe Acquired Brain Injuries
Severe Acquired Brain Injury is defined as a traumatic, post-anoxic, vascular or other brain damage that causes coma for at least 24 hours and leads to permanent disability with sensorial, motor, cognitive or compartmental impairment. In this context, an accurate characterization of individual patients' profile in terms of neuronal damage, …
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- 19 Feb, 2024
- 1 location
Place of Intrathecal Analgesia to Improve the Quality of Life of Painful Cancer Patients
The intrathecal analgesia is a recommended technic to treat persistent pain in cancer patient but little used, whose the technical conditions require hospital multidisciplinary expertise and coordination associated to a link between city and hospital.
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- 19 Feb, 2024
- 3 locations
Bone Pain in Multiple Myeloma- a Translational Study
Primary research questions: How is the bone pain experienced by myeloma patients (intensity, location and type of pain) and how does it affect their quality of life? Do myeloma cells induce changes in the density and/or location of nerve fibres innervating the bone, and if so, are these correlated to …
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- 19 Feb, 2024
- 1 location