Found 1317 clinical trials
Brentuximab Vedotin Plus Lenalidomide and Rituximab for the Treatment of Relapsed/Refractory DLBCL
All patients in the study will get rituximab and lenalidomide. These are drugs that can be used to treat DLBCL.
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- 19 Feb, 2024
Phase I Study in Advanced Malignancies
RDT aims to take advantage of the relatively safer toxicity profiles of both lower dose radiation therapy and systemic ALA to treat non-superficial lesions in a manner similar to photodynamic therapy. The doses of radiation administered in this study will be lower than those typically used to treat cancer. However, …
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- 19 Feb, 2024
SubsTRate OxidatioN in Girls
This study will examine race differences in total energy expenditure and respiratory quotient (RQ) during and after exercise, compared to a sedentary control condition, in adolescent girls who are classified as overweight. In addition, subjective appetite will be measured throughout the assessment periods.
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- 19 Feb, 2024
A Study to Investigate the Pharmacokinetics Efficacy and Safety of INM005 in Patients With COVID-19.
Improvement of the clinical course 28 days after the start of treatment will be evaluated.
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- 19 Feb, 2024
The Influence of a Perturbation Training on Balance Recovery of Old Adults: a Randomized Controlled Trial
We hypothesize that response to an unexpected loss of balance is the balance responses will be improved in both training methods, but more in the random training method. We also hypothesize that brain function as seen in MRI will be improved in both training methods, more in the random training …
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- 19 Feb, 2024
TACE Combined With PD-1 Knockout Engineered T Cell in Advanced Hepatocellular Carcinoma.
This study will evaluate the safety and effect of transcatheter arterial chemoembolization (TACE)combined with percutaneous transhepatic PD-1 knockout engineered T cell infusion in the Paitents with advanced hepatocellular carcinoma(HCC). Blood and tissue samples will also be collected for research purposes.
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- 19 Feb, 2024
Injections of Glutamic Acid Decarboxylase (GAD) for LADA Type of Diabetes
This study will evaluate the effects of 3 intra-nodal injections of GAD-alum (Diamyd), together with oral vitamin D supplementation. Safety and feasibility of the treatment will be evaluated and also effects on the immune system and on the preservation of endogenous insulin production.
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- 19 Feb, 2024
AAV Gene Therapy Study for Subjects With PKU
Participants will receive a single administration of BMN 307 and will be followed for safety and efficacy.
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- 19 Feb, 2024
A Study to Test the Effects and Safety of Riliprubart in People With Chronic Inflammatory Demyelinating Polyneuropathy (CIDP) for Which the Usual Treatments do Not Work (MOBILIZE)
The purpose of the study is to evaluate efficacy of riliprubart compared to placebo in adult participants with CIDP whose disease is refractory to standard of care. The study duration will be for a maximum of 109 weeks including screening, treatment phases, and follow-up.
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- 06 Feb, 2025
CCCG Relapsed Acute Lymphoblastic Leukemia 2017 Study in Children
New agents will be added aiming at improving survival outcome. Study of adding anti-CD20 antibody (rituximab) with chemotherapy: CD20 is found to be expressed in 40-50% of B-lineage ALL, and rituximab has been studied in adult ALL with superior survival (75% vs 47%,).
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- 19 Feb, 2024