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Found 1278 clinical trials
Development of an Algorithm to Differentiate Heart Murmurs Using Electronic Stethoscopes

The Eko CORE and DUO stethoscopes are FDA-approved electronic devices that have the capacity to record heart sounds. The study seeks to expand murmur detection to include VHD classification through the development of novel ML algorithms that are able to distinguish between systolic vs. diastolic vs. continuous murmurs, as well …

heart sounds
auscultation
  • 0 views
  • 19 Feb, 2024
  • 1 location
Differentiated Service Delivery for Antiretroviral Therapy

This study is a prospective observational cohort. The target study population is PLHIV who receive ART at hospitals and community-based organizations (CBOs) in Chiang Mai, Ubon Ratchathani, Chonburi, and Songkhla. Participants will receive ART service in the same standard as in the hospital setting. Secondary data will be collected from …

antiretroviral agents
antiretroviral therapy
  • 0 views
  • 19 Feb, 2024
  • 1 location
BESPOKE Study of ctDNA Guided Therapy in Colorectal Cancer

The BESPOKE CRC study will prospectively enroll patients who have undergone surgery for stage II or III colorectal cancer (CRC) and who have residual formalin-fixed paraffin-embedded (FFPE) tissue available will provide FFPE and whole blood samples. Patients will receive SIGNATERA test results and may be recommended for adjuvant chemotherapy or …

cancer
adjuvant
colorectal cancer
adenocarcinoma of colon
formalin-fixed paraffin-embedded
  • 0 views
  • 19 Feb, 2024
  • 17 locations
Outcome of Patients Treated With RRT

Acute Kidney Injury (AKI) is a common serious complication after cardiac surgery. AKI not only prolongs the hospitalization time of patients undergoing cardiac surgery and increases the cost of treatment, but also is an independent risk factor for postoperative death. The aim of this study is to investigate the outcome …

critical illness
replacement therapy
renal replacement
critically ill
kidney injury
  • 0 views
  • 19 Feb, 2024
  • 1 location
Precision Therapy in Complex High-risk Coronary Artery Disease

This is a prospective registry to enroll complex high-risk coronary heart disease patients. The purpose of this study is to compare intracoronary physiology and imaging-guided intervention strategy and angiography-guided intervention strategy for clinical outcomes and health economics.

ejection fraction
in stent restenosis
stent restenosis
angiography
arterial disease
  • 0 views
  • 19 Feb, 2024
  • 1 location
Clinical Study on Raman Spectra of Blood Saliva and Urine in Patients With Cancer Treated by Modern Therapy

Blood, saliva and urine samples of tumor patients on the day of admission and discharge were collected for Raman spectral analysis, which provided exploration for the prediction of efficacy, follow-up and prognosis according to the variation characteristics of Raman spectral.

cancer
targeted therapy
  • 0 views
  • 19 Feb, 2024
  • 1 location
Application of Radiomics in Breast Cancer

Little is known about the correlation between ultrasound characteristics (conventional, elastography and contrast enhanced ultrasound (CEUS) )and pathological prognostic factors in breast cancer. The aim of this study was to explore the correlation between ultrasound characteristics and pathological prognostic factors using radiomics.

cancer
ultrasound elastography
hormone therapy
breast cancer
contrast-enhanced ultrasound
  • 0 views
  • 19 Feb, 2024
  • 1 location
Prospective Cohort Study of Carbon Monoxide Poisoning in Wonju Severance Christian Hospital

This prospective cohort study enrolls subjects who experience carbon monoxide (CO) poisoning. The purpose of the study is to evaluate therapeutic effects of various treatments and short and long-term outcomes in CO poisoned patients. In addition, complications of brain and heart susceptible to CO are investigated through various ways and …

hyperbaric oxygen
cardiac mri
myocardial injury
carbon monoxide
  • 0 views
  • 19 Feb, 2024
  • 1 location
Th1/Th2/Th17/TREG and TLRs Activation/KIR for COVID 19 Prediction of Outcome

To ascertain globally the changes in the cytokines involved and TLRs/KIR activation in patients admitted to the hospital with a COVID-19 diagnosis, and the changes after initiation of the different therapies

cytokines
covid-19
  • 0 views
  • 19 Feb, 2024
  • 1 location
Development and Analysis of a Stool Bank for Cancer Patients

This study is aimed at understanding the impact of gut microbiota on efficacy of cancer therapies, in particular checkpoint inhibitors, and using the resulting information to design microbial immunotherapies. Although animal models are of use to determine the influences of gut and other microbiota on cancer treatment modalities, they are …

pembrolizumab
immunotherapies
cancer treatment
cancer immunotherapy
  • 0 views
  • 19 Feb, 2024
  • 2 locations