Found 1411 clinical trials
Assessment of Salivary GM-CSF, MIP, and IL-1β Levels in Subjects With Varying Periodontal Conditions
All oral clinical parameters of 60 systemically healthy individuals (20 healthy, 20 with gingivitis and 20 with periodontitis) who applied to our clinic for routine periodontal control will be measured and saliva samples will be taken from the patients. GM-CSF, MIP-1α and IL-1β (biomarkers emphasizing inflammation in saliva samples) will …
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- 08 May, 2025
Prospective Trial for the Evaluation of Radiogenomics in Advanced Rectal Cancer
In patients with advanced rectal cancer, molecular subtypes will be identified by preoperative biopsy, CT, MRI / PET radiomics analysis, clinical features, and clinical features will be confirmed and compared.
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- 19 Feb, 2024
- 1 location
Natural History Study of Children and Adults With Neuroendocrine Neoplasms (NEN)s
Eligibility People starting at age 3 and older who have or are suspected of having NENs and are enrolled in protocol 19C0016, Natural History and Biospecimen Acquisition Study for Children and Adults with Rare Solid Tumors Design Participants will be screened with questions about their medical history. This may be …
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- 19 Feb, 2024
- 1 location
Metabolomic and Proteomic Fingerprinting in Peri-implant Diseases
One year after the corresponding treatment is provided, the PICF of the treated implants with peri-implantitis will be sampled again. Both proteomic and metabolomic profiling of the samples will be carried out. The most important strength of this project will be the ability to evaluate together the whole proteome and …
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- 19 Feb, 2024
- 1 location
Postoperative Neurocognitive Disorders
The Confusion Assessment Method (CAM-S) test, will be used to examine postoperative delirium.
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- 19 Feb, 2024
- 1 location
Is COVID-19 Transmitted Through Human Milk? Implications for Breastfeeding and Human Milk Banking-Study 1b
This study seeks to address this public health issue. Donor milk will be collected from the Rogers Hixon Ontario Human Milk Bank at Sinai Health System in Toronto. Samples will be analyzed for the COVID-19 virus specific nucleic acid and antibody in real-time and results will be immediately disseminated to …
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- 19 Feb, 2024
- 1 location
RadioPathomics Artificial Intelligence Model to Predict nCRT Response in Locally Advanced Rectal Cancer
By the system, whether the participants achieve the pathologic complete response (pCR) will be identified based on the radiopathomics features extracted from the pre-nCRT Magnetic Resonance Imaging (MRI) and biopsy images. The predictive power to discriminate the pCR individuals from non-pCR patients, will be validated in this multicenter, prospective clinical …
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- 19 Feb, 2024
- 3 locations
Trajectory of Microbiota Maturation in Healthy Bern Infants - a Network Approach
Methods: The investigators will recruit 120 pregnant mothers who will be followed as mother-baby pairs until 10 years of age. Infants will be followed clinically to determine adequate growth and development as well as pathology including abdominal pain.
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- 19 Feb, 2024
- 1 location
Gait Analysis of a Lateral-Pivot Design Total Knee Replacement
These data will be compared with data previously collected from patients who received Stryker Triathlon devices, Biomet Vanguard devices and age-matched healthy control subjects.
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- 19 Feb, 2024
- 1 location
Advanced Geriatric Evaluation and Quality of Life in Colorectal Cancer Surgery
Surgery is the main treatment modality for CRC, but is associated with increased risk of postoperative morbidity, disability and loss of health related quality of life (HRQL).Frailty is an age related state of functional decline and considered to be an important risk factor for adverse outcome in geriatric oncology.Risk models …
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- 19 Feb, 2024
- 6 locations