Found 1376 clinical trials
ABCB1/P-glycoprotein Expression Influence on Non-metastatic Osteosarcoma of the Extremities
After surgical treatment, the histological response to neoadjuvant chemotherapy will be evaluated. The histological response to primary chemotherapy will be expressed as a percentage of tumor necrosis. In the case of tumor necrosis above 90% the patient is defined as a "good responder" in case of a lower percentage as …
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- 19 Feb, 2024
- 17 locations
Clinical Scores for Outcome Prediction in Patients With Severe COVID-19 Pneumonia Requiring ECMO
This is aggravated by the fact that even at very specialized centers only very few patients from this collective are (can be) treated, so that valid investigations are only possible in a multicenter patient collective. In this registry study, all patients diagnosed with COVID-19 and treated with vv-ECMO in the …
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- 19 Feb, 2024
- 1 location
Hyperlactatemia During and After Tumorcraniotomy
This study aims to investigate the association between hyperlactatemia and neurological disability, length-of-stay and mortality in patients who undergo tumorcraniotomy. The risk factors that induce lactat accumulation will also be explored.
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- 19 Feb, 2024
- 1 location
The Role of Micrometastasis and Isolated Tumor Cells (ITCs) in Endometrial and Cervical Cancer. A Multicenter Study.
Data on type and volume of lymph nodal disease, therapeutic choices and oncological outcomes (DFS, OS, recurrence rate) will be collected and analyzed. This will allow to define the groups of patients who may need or for whom it can be avoided any adjuvant treatment on the basis of lymph …
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- 19 Feb, 2024
- 1 location
Health and Employment After Gastro Intestinal Surgery - HEAGIS2
The research will implement an instrument for the purpose of measuring the health need of participants who are admitted to the surgical ward. Therefore, targeted interventions will be implemented with participants, and efficacy will be evaluated in order to define treatment guidelines. The principal aim of this study is to …
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- 19 Feb, 2024
- 2 locations
COronary and MICrocirculatory Measurements in Patients With Aortic Valve Stenosis.
These measures of CAD severity will be compared with a gold standard non-invasive test (single photon emission computed tomography [SPECT]). This will validate the use of RFR and determine if IMR can be used to improve the ischemia prediction of FFR.
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- 19 Feb, 2024
- 1 location
Hemodynamic Changes Due to Prone Position
Perioperative prone position may be associated with hemodynamic instability. The causes of instability have not yet been precisely elucidated. The aim of this study is to demonstrate physiological changes during prone positioning in healthy volunteers .
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- 19 Feb, 2024
- 1 location
New Daily Persistent Headache Biomarkers Study
If CGRP levels are elevated in the blood of people with new daily persistent headache, future studies will be designed to evaluate whether treatments that target CGRP are effective in treating new daily persistent headache. If NGF levels are elevated in the blood of patients with new daily persistent headache …
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- 19 Feb, 2024
- 1 location
Anesthesia Consent Process
Currently at University of Chicago Medical Center (UCMC) consent for anesthesia is obtained verbally by qualified anesthesia providers. Later this year, we will be moving to a written informed consent form for anesthesia that must be signed by patients before proceeded with elective surgery. We aim to study patient satisfaction …
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- 02 Dec, 2024
- 1 location
Maternal Psychological Implications of Covid-19 Pandemic and Possible Effect on Anaesthetic Management.
The aim of this study is to assess the maternal psychological implication of the novel coronavirus COvid-19 pandemic. At the same time it will be evaluated whether there is an impact of these implications on the anaesthetic practice.
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- 19 Feb, 2024
- 1 location