Found 1269 clinical trials
Neoadjuvant Chemotherapy in Borderline Resectable and Locally Advanced Pancreatic Cancer
Eligible patients are treated with neoadjuvant chemotherapy possibly followed by surgical exploration and resection. All Norwegian centres performing pancreatic surgery have agreed to collaborate in this trial. The assignment of the medical intervention is not at the discretion of the investigator, but follow the national Norwegian guidelines regarding diagnostic work …
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- 19 Feb, 2024
- 1 location
Understanding the Transition from Normal Melanocytes to Nevus to Melanoma (NevustoMel)
The primary objective of this study is to identify the molecular identity profiles of all cellular states that characterize the progression from benign nevi to malignant melanoma in CAYA patients with L/GCMN. The secondary objectives are:To longitudinally characterize the cell-free DNA (cfDNA) from CAYA patients.
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- 06 Feb, 2025
Childhood Allergy and the Neonatal Environment
Previous birth cohort studies have found early-life environmental factors such as allergies, pollutants, viruses and bacteria have all contributed to the development of asthma and allergies. Investigators are doing this research because there continues to be a strong need to understand the root causes of asthma and allergies.
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- 19 Feb, 2024
- 4 locations
Classification of Benign and Malignant Lung Nodules Based on CT Raw Data
The employ of medical images combined with deep neural networks to assist in clinical diagnosis, therapeutic effect, and prognosis prediction is nowadays a hotspot. However, all the existing methods are designed based on the reconstructed medical images rather than the lossless raw data. Considering that medical images are intended for …
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- 19 Feb, 2024
- 1 location
Detection of Metabolite Biomarkers for the Early Diagnosis and Prognosis of Cow's Milk Allergy in Children
Additionally, microbiome analysis will be performed to map the microbiome of all groups.
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- 19 Feb, 2024
- 8 locations
Investigation of Antibody and Immune Responses to SARS-CoV-2 Proteins
Samples you provide will be used investigationally by INanoBio to develop a test to determine when antibodies against various SARS-CoV-2 proteins are detectable. Up to approximately 80 subjects of all ages with either a suspected or lab-confirmed diagnosis of COVID-19 will take part in this research.
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- 19 Feb, 2024
- 1 location
ABCB1/P-glycoprotein Expression Influence on Non-metastatic Osteosarcoma of the Extremities
And, in some hospitals, they will consider administering MTP-PE to all patients.
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- 19 Feb, 2024
- 17 locations
3D Characterisation of the Skull Base Deformation in Congenital Muscular Torticollis
The hypothesis of a traction force on the base of the skull from the SCM could explain most of all the asymmetrical deformatios encountered in CMT. It would be associated to a compression force at the occipital level
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- 19 Feb, 2024
- 1 location
Postoperative Neurocognitive Disorders
The investigators will enroll 50 OSA patients scheduled for surgery. All patients will have a brain scan (fMRI) within five days before surgery and two days and six months after surgery. During this visit cognitive function will be assessed using the Wide Range Assessment of Memory and Learning (WRAML2) and …
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- 19 Feb, 2024
- 1 location
Study on Susceptibility Genes and Pathogenic Mechanism of Non-syndromic Familial Aortic Dissection
The related genes found in previous studies can not be detected in all patients with dissection; at present, the pathogenesis of non-syndromic aortic dissection is not clear, of which about 20% of patients have family aggregation and have the general representative characteristics of non-syndromic dissection.
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- 19 Feb, 2024
- 1 location