Found 1260 clinical trials
The Effect and Mechanism of lncRNA NBR2 Regulating Endothelial Pyroptosis by Targeting GSDMD in Sepsis
Gasdermin D (GSDMD) mediated endothelial pyroptosis plays a critical role in modulating vascular endothelial injury in sepsis. Long non-coding RNA (lncRNA), as a class of non-coding protein RNA longer than 200 kD, contributes to a variety of cell biological processes. The dysregulation of lncRNA results in the occurrence and development …
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- 19 Feb, 2024
- 1 location
Interest of a Period of Fasting Before Extubation in Resuscitation Patients
The hypothesis is that continued enteral nutrition before extubation is associated with increased gastric volume as measured by ultrasound.
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- 19 Feb, 2024
- 1 location
Cardiac Biomarkers in Preeclampsia: Prediction of Disease and the Risk of Future Cardiovascular Events in Survivors
Data Analysis: would be performed using the Statistical Package for Social Sciences (SPSS) software version 21.0. Numerical data would be expressed as mean standard deviation (SD). Results from the two groups of women would be compared using the independent T-test, Analysis of Variance (ANOVA) and the chi-square test while the …
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- 19 Feb, 2024
- 1 location
Early Diagnosis of Upper Digestive Tract Disease
Exhaled breath testing is a non-invasive and acceptable technology utilising mass spectrometry (MS) which has shown promise at diagnosing cancer at an early stage. Previous research has shown that products formed as a result of metabolism can be measured in breath and saliva (biomarkers). This has the ability to accurately …
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- 19 Feb, 2024
- 1 location
Evaluation of the Satisfaction of Patients Coming "on Foot" in the Operating Room
In this context, the optimization of the whole patient's journey during the perioperative period has been reviewed and adapted to personalized management within healthcare facilities. For more than a year now, multimodal approaches such as early rehabilitation have been undertaken, including morning admission with an innovative principle of "3D" patient …
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- 19 Feb, 2024
- 5 locations
Natural History Study of Children and Adults With Adrenocortical Cancer (ACC)
Participants home physician will be contacted every 6 to 12 months to collect medical information such as test results and scans. Participants may be asked to return to the NIH every 6 to 12 months for follow-up tests. Participants will contact study staff if there are any changes in their …
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- 19 Feb, 2024
- 1 location
Natural History Study of Children and Adults With Neuroendocrine Neoplasms (NEN)s
Participants home doctors will be contacted every 6 to 12 months. They will give medical data such as imaging and test results. Participants may have follow-up visits at NIH every 6 to 12 months. Participants will contact researchers if there are any changes in their tumor.
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- 19 Feb, 2024
- 1 location
COVID-19 in Cancer Patients: Evaluation of Clinical Course and Impact on Oncological Care Including Biobanking
The COVIDHELP study will prospectively evaluate the yet unknown clinical course of the COVID-19 infection in cancer patients and document the impact of potential infrastructural limitations on cancer care of COVID-19 positive patients. All patients consenting will provide peripheral blood samples for prospective biobanking with the aim of investigating immune …
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- 19 Feb, 2024
- 1 location
Effect of Oxalate and Urate Metabolism on CKD Evolution
The current study primarily aimed to characterize the oxalate and uric acid metabolism in CKD patients and to analyze its association with renal survival prognosis. Secondarily, the study is planned to determine whether hyperoxalemia and hyperuricemia are independent risk factors for cardiovascular events and mortality.
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- 19 Feb, 2024
- 1 location
Preoperative Shielding and N/T RT-PCR Swabbing for Elective Cancer Surgery
trial to assess the effectiveness of pre-operative screening for COVID-19 in patients undergoing elective cancer surgery.
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- 19 Feb, 2024
- 1 location