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Found 1260 clinical trials
Feasibility of Non-Operative Management of Rectal Cancer in a Rural Population

The surveys will analyze the impact of the patients' treatment choices, as well as patient adherence, in a rural setting.

cancer
rectal cancer
proctectomy
  • 0 views
  • 19 Feb, 2024
  • 1 location
Epileptic Activity in Patients With Alzheimer's Disease and Lewy Body Dementia

Furthermore, the investigators want to investigate whether there is an association between subclinical epileptic activity and the cerebral blood flow as measured with functional MRI.

depressive symptoms
epilepsy
lewy body dementia
dementia
selective serotonin reuptake inhibitors
  • 0 views
  • 19 Feb, 2024
  • 2 locations
Heart Failure Monitoring With Eko Electronic Stethoscopes

This proof-of-concept study will evaluate the feasibility of the Eko DUO to measure signals relevant to heart failure (HF) decompensation, as well as the feasibility to develop an algorithm to model hemodynamic filling pressures in HF patients under active decompensation in a cardiac intensive care unit (CICU) or coronary care …

decompensated heart failure
adhf
hemodynamic measurements
heart failure
acute decompensated heart failure
  • 0 views
  • 19 Feb, 2024
  • 1 location
A Naturalistic Study of Functional Impairment for Individuals With ADHD in the Early Morning and Late Afternoon/Evening Hours

This is necessary for two reasons: (1) the current literature on ADHD impairment and functioning is concentrated within elementary school children; and (2) studies of intervention effectiveness are typically concentrated during the school day. This current state of the literature ignores the obvious - as ADHD is a chronic disorder, …

chronic disease
attention deficit hyperactivity disorder
pervasive developmental disorder
psychiatric disorder
psychosis
  • 0 views
  • 19 Feb, 2024
  • 1 location
Development and Analysis of a Stool Bank for Cancer Patients

Although animal models are of use to determine the influences of gut and other microbiota on cancer treatment modalities, they are limited due to differences between mouse and human physiology and immunology, as well as the inherent differences in gut microbial populations between the two mammalian organisms. Therefore, samples obtained …

cancer immunotherapy
immunotherapies
cancer treatment
pembrolizumab
  • 0 views
  • 19 Feb, 2024
  • 2 locations
COVID - AirPollution

In this multicenter prospective study, the investigators will analyze the number of deaths in COVID-19 confirmed cases in geriatric patients according to long-term exposure to air pollution, taking into account confounders such as diabetes, hypertension, age, and BMI. Exposure to air pollution will be estimated as the mean concentration of …

  • 0 views
  • 19 Feb, 2024
  • 11 locations
The Effect of Pediatric Patient Temperament on Postoperative Outcomes

This is a prospective observational study to assess preoperative temperament in pediatric patients undergoing tonsillectomy and adenoidectomy, gather demographic data, intraoperative data regarding surgical and anesthetic technique, and collect immediate postoperative data to assess pain, emergence agitation (EA), parental satisfaction as well as remote postoperative data to assess emotional and …

tonsillectomy
pain assessment
behavioral disturbances
adenoidectomy
pediatric
  • 0 views
  • 19 Feb, 2024
  • 1 location
Trajectory of Microbiota Maturation in Healthy Bern Infants - a Network Approach

Methods: The investigators will recruit 120 pregnant mothers who will be followed as mother-baby pairs until 10 years of age. Infants will be followed clinically to determine adequate growth and development as well as pathology including abdominal pain.

placenta
diabetes
hypertension
mass spectrometry
microbiota
  • 0 views
  • 19 Feb, 2024
  • 1 location
Retention and Durability of the Anterior Zirconia Wing Bridge

The type of zirconia-wing bridge the investigators are researching in this study has two wings which generally have three countersunk holes (meaning that the circumference of the outer portion of the hole is larger than the inner part of the hole). Composite resin (dental filling material) is placed in the …

dental filling
  • 0 views
  • 19 Feb, 2024
  • 1 location
ABCB1/P-glycoprotein Expression Influence on Non-metastatic Osteosarcoma of the Extremities

The histological response to primary chemotherapy will be expressed as a percentage of tumor necrosis. In the case of tumor necrosis above 90% the patient is defined as a "good responder" in case of a lower percentage as a "poor responder".

ifosfamide
localized disease
p-glycoprotein
tumor necrosis
adjuvant therapy
  • 0 views
  • 19 Feb, 2024
  • 17 locations