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Found 11074 clinical trials
A Study to Assess the Long-Term Safety of Ustekinumab Versus Other Biologics in Patients With Crohn's Disease

The purpose of this study is to estimate and compare the incidence of overall malignancy, serious infection, and opportunistic infections between new users of ustekinumab and new users of other biologic therapies among adult participants with Crohn's disease (CD).

biologics
crohn's disease
ustekinumab
opportunistic infection
cancer
  • 0 views
  • 19 Feb, 2024
GROWing Up With Rare GENEtic Syndromes

Therefore, pediatricians express the urgent need for adequate, multidisciplinary adult follow up of their pediatric patients with rare genetic syndromes. Medical guidelines for adults not exist and the literature on health problems in these adults is scarce.

congenital diseases
rare diseases
intellectual disability
pediatric
genetic disorder
  • 0 views
  • 19 Feb, 2024
A Study of Patients With Chronic Disease

TARGET-RWE is a 10-year, international, longitudinal, observational study of patients with chronic disease designed to specifically address important clinical questions that remain incompletely answered from registration trials. The protocol will follow a master protocol design in which a shared study infrastructure supports progressive development of the registry across the spectrum …

chronic disease
a 10
  • 0 views
  • 19 Feb, 2024
Prospective Longitudinal Observational Research in Atopic Dermatitis

Atopic dermatitis (AD) is a frequent chronic relapsing inflammatory skin disorder, characterized by intensely itchy eczema. AD usually starts within the first 2 years of life. In 30 - 60% of children, inflammation spreads onto other body surfaces such as the gastrointestinal tract, the respiratory tract, and the conjunctives within …

rhinitis
atopic dermatitis
atopy
dermatitis
asthma
  • 0 views
  • 19 Feb, 2024
PROtocol of Metabolic and Cryptogenic livEr Disease regisTry for intEgration of Omic Studies

The main aim of the study is to set up an observational cohort with NAFLD (Non-alcoholic fatty liver disease) at different stage of disease (from simple steatosis to cirrhosis and/or HCC-Hepatocellular carcinoma) and for comparative purpose a cohort of subjects with diabetes and/or obesity and/or other risk factors (i.e. psoriasis, …

cirrhosis
hcv infection
non-alcoholic fatty liver
hepatocellular carcinoma
dyslipidemia
  • 0 views
  • 19 Feb, 2024
The European NAFLD Registry

The European NAFLD Registry is a prospectively recruited, observational study supporting the study of the clinical phenotype, natural history, disease outcomes and pathophysiology of Non-Alcoholic Fatty Liver Disease and Non-Alcoholic Steatohepatitis. The ultimate goals are to better understand the drivers of interpatient variation in disease pathophysiology and severity and to …

glycosylated hemoglobin
cirrhosis
nonalcoholic steatohepatitis
niddm
non-alcoholic fatty liver
  • 0 views
  • 19 Feb, 2024
Asthma Research in Children and Adolescents

The purpose of this study is to assess the evolution of disease control, health-related quality of life, and the risk of severe asthma exacerbations in children and adolescents with persistent asthma in Spain at short, mid and long-term follow-up. Patient-reported information in this project is collected by computer assisted telephone …

corticosteroids
asthma
computer assisted
inhalation technique
  • 0 views
  • 19 Feb, 2024
Venous Disease in Pediatric Population

Chronic venous disease (CVD) is widespread in adult subjects of western countries and is responsible of important morbidity and healthcare costs. CVD has never been extensively studied in pediatric population where the early pathophysiological alterations may occur undetected. The aim of this study is to assess the prevalence of CVD …

venous disease
pediatric
  • 0 views
  • 19 Feb, 2024
The Effect of Pediatric Patient Temperament on Postoperative Outcomes

This is a prospective observational study to assess preoperative temperament in pediatric patients undergoing tonsillectomy and adenoidectomy, gather demographic data, intraoperative data regarding surgical and anesthetic technique, and collect immediate postoperative data to assess pain, emergence agitation (EA), parental satisfaction as well as remote postoperative data to assess emotional and …

adenoidectomy
tonsillectomy
agitation
postoperative pain
pain assessment
  • 0 views
  • 19 Feb, 2024
Design and Implementation of the Pediatric Liver Transplantation Biobank

The purpose of the pediatric liver transplant biobank is to systematically collect clinical specimens from pediatric end-stage liver disease. It is expected to contribute to the research and development of paediatric end-stage liver disease in the future.

liver transplant
liver disease
pediatric
  • 0 views
  • 19 Feb, 2024