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Found 1317 clinical trials
New Intervention Protocol With Inspirometer Versus 2 Modalities of Pulmonary Intervention: INSPUL-REHAB

A clinical trial will be carried out in the area of physiotherapy and rehabilitation of the "Centro Integral de Rehabilitacin S.C. at the Hospital Angeles Lomas" in Mexico.

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  • 19 Feb, 2024
Moxidectin for LF Cote d'Ivoire (DOLF)

The purpose of this study is to determine whether moxidectin (Mox) will be more effective than ivermectin (IVM) when used in single-dose combination therapies for lymphatic filariasis (LF).

ivermectin
lymphatic filariasis
combination therapy
antifilarial
filariasis
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  • 19 Feb, 2024
Safety of Manganese Restriction in Neonatal Parenteral Nutrition

Participants will be <= 32 weeks gestational age (GA) neonates randomized to parenteral nutrition (PN) prepared with standard dose trace elements or to PN prepared with standard trace elements minus manganese.

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  • 19 Feb, 2024
Dose Escalation Study of PF-07209326 in Healthy Participants

This Phase 1 first-in-human single ascending dose and multiple dose study will be a randomized, double-blind, placebo-controlled investigation of the safety, tolerability, and pharmacokinetics of PF-07209326.

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  • 19 Feb, 2024
PHP and Immunotherapy in Metastasized UM

In this study a combination therapy with immunotherapy (ipilimumab with nivolumab) and chemotherapy (melphalan) will be assessed for the treatment of disseminated uveal melanoma. Melphalan will be administered selectively to the liver via percutaneous hepatic perfusion, limiting the systemic effect of chemotherapy.

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  • 19 Feb, 2024
Study of the Safety and Effectiveness of GSK6097608 in Participants With Advanced Solid Tumors

Approximately 100 adult participants with locally advanced, recurrent, or metastatic solid tumors will be enrolled.

solid neoplasm
measurable disease
ejection fraction
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  • 19 Feb, 2024
Comparison of 2 Different Positional Therapies for Positional Obstructive Sleep Apnea Syndrome

The effectiveness of the two different therapeutic devices (Positional pillow and vibrating belt) in reducing the time spent sleeping supine, and therefore at risk of apnoeas, will be evaluated consecutively in 52 subjects with a de novo diagnosis of positional sleep apnoea. The subjective quality of sleep will also be

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  • 19 Feb, 2024
BREast Cancer And Sexuality Treatment

Groups will consist of approximately 8 breast cancer survivors and will be led by 2 trained therapists. Participants will complete four assessments (involving a clinician administered interview and standardized questions): pre-treatment, post- treatment, and 6 month follow up.

breast cancer
cancer
pain in breast
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  • 19 Feb, 2024
1 march 4  

Based on the Stage 1 analysis performed in November 2014, Arm 1 was chosen for expansion in Stage 2. Stage 2 dose will be 1-5x10xE8 transduced CART-19 cells. The dose of 1-5 x 10xE8 T-cells in Stage 2 will be administered via split dosing: 10% on Day 1 (1-5x10xE7), 30% …

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  • 19 Feb, 2024
  • 1 location
Clinical Trial of YH25448(Lazertinib) as the First-line Treatment in Patients With EGFR Mutation Positive Locally Advanced or Metastatic NSCLC (LASER301)

This Phase III study will be conducted to evaluate the efficacy and safety of YH25448 as first-line treatment in locally advanced or metastatic Non-small Cell Lung Cancer (NSCLC) patients with EGFR mutations

curative surgery
lung adenocarcinoma
EGFR
small cell lung cancer
adenocarcinoma
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  • 19 Feb, 2024