Found 1376 clinical trials
Autoantibodies Prevalence During Checkpoint Inhibitor Treatment
Clinical trials using ICIs have largely excluded patients with preexisting autoimmune diseases but the rate of autoimmune flares has been reported to be high in patients with preexisting autoimmune diseases in retrospective cohort studies. Moreover numerous retrospective cases and series reported ICI-related autoimmune diseases in patients without any previous autoimmune …
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- 19 Feb, 2024
- 1 location
CT-guided Stereotactic Body Radiation Therapy and MRI-guided Stereotactic Body Radiation Therapy for Prostate Cancer MIRAGE Study
Image-guided SBRT is a standard treatment for prostate cancer, which combines imaging of the cancer within the body with the delivery of therapeutic radiation doses produced on a linear accelerator machine. Imaging modalities for image-guided SBRT can be either computed tomography imaging (CT), magnetic resonance imaging (MRI), or a combination …
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- 19 Feb, 2024
- 1 location
Layer-specific Contribution to Consolidation of Skill Learning in the Primary Motor Cortex
Design Participants will be screened with: Medical and neurological history Medicine review Physical exam Neurological exam.
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- 19 Feb, 2024
- 1 location
Validation of Continuous Transcutaneous Carbon Dioxide Monitoring in VA-ECMO Patients
Continuous, rapidly applicable monitoring of reliable carbon dioxide measures would therefore be extremely helpful to prevent harmful deviations from the norm. The investigators therefore try to assess the accuracy and the precision of continuously measured non-invasive transcutaneous carbon dioxide partial pressures when compared with tensions determined by blood gas analysis.
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- 19 Feb, 2024
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DWIBS-MRI: An Adjunct to the Traditional Diagnostic Breast Imaging Evaluation
Primary Objectives To determine if MRI DWIBS can accurately identify suspicious lesions previously categorized on mammography and sonography as potentially malignant. We will also validate whether DWIBS-MRI ADC values can be used to accurately differentiate benign from malignant lesions. Additionally, because it is not known whether tumor type or growth …
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- 19 Feb, 2024
- 1 location
Attentional Performance in Parkinson Disease
Design Participants will be screened with medical and neurological history and exam, and medicine review. Participants will have 1 study visit. It will last 7-8 hours.
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- 19 Feb, 2024
- 1 location
Cardiovascular Consequences After COVID-19
The occurrence of cardiovascular complications in SARS-CoV-2 infections appears to be more frequent than in other viral respiratory infections, probably due to a singular pathophysiology of this coronavirus. The lack of characterization of cardiovascular damages linked to Covid-19 could have medium and long-term consequences on the prognosis of patients.
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- 19 Feb, 2024
- 1 location
Comparison Between the Old Diagnostic Tools for Paediatric Undernutrition and the HAS Recommendations
Until now, there has been no national consensus on the criteria to be used to diagnose paediatric undernutrition. Until now, assessment focused on a range of non-consensus arguments that allowed the health care team to make its diagnosis.
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- 19 Feb, 2024
- 1 location
Dietary Diversity of Young Children During CoVID-19 Outbreak: A Longitudinal Study
The 2019-2020 coronavirus pandemic has had far-reaching consequences beyond the spread of the disease. Quarantine measures during a public health pandemic can be particularly detrimental to urban poor families and affect the dietary diversity and food security. This can disproportionately affect young children aged 6 and below, and severely impact …
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- 19 Feb, 2024
- 1 location
Direct Effect of Caffeine on Diaphragmatic Muscles
Right and left sides of diaphragm thickness are being measured by two clinicians on B mode ultrasound by anterior subcostal view. The velocity before and after caffeine administration will be calculated, dividing excursion frequency (parameter) for inspiratory time. Movement of the diaphragm at inspiratory and expiratory phases are also observed …
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- 19 Feb, 2024
- 1 location