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Found 20 clinical trials
Histopathologic Effect of Calcium Electroporation on Cancer in the Skin

In this phase II study we investigate the effect of calcium electroporation on cancer in the skin investigated by histopathology.

endocrine therapy
hormone therapy
calcium
cancer
metastasis
  • 0 views
  • 19 Feb, 2024
  • 1 location
Reduced Radiation Dose and IR-impact on Coronary Calcium Quantification

Evaluation of reduced radiation dose iterative reconstruction reconstructions for calcium scoring compared to full dose filtered back projection reconstructions

  • 0 views
  • 19 Feb, 2024
  • 1 location
  • 0 views
  • 19 Feb, 2024
  • 1 location
A Study to Evaluate the Efficacy Safety and Tolerability of IMU-838 as Addition to Investigator's Choice of Standard of Care Therapy in Patients With Coronavirus Disease 19 (COVID-19)

In this study we plan to investigate if an experimental drug called IMU-838 (vidofludimus calcium) can improve your symptoms, prevent worsening that would initiate further treatments such as ventilation, and can lower your virus number if given in addition to your doctor's choice of standard therapy.

cough
fever
estrogen
SARS
covid-19
  • 0 views
  • 19 Feb, 2024
  • 4 locations
Effect of Cassia Cinnamon on Arterial Stiffness Parameters in Patients With Type 2 Diabetes Mellitus

Cassia cinnamon pulverized bark has demonstrated to have vasodilator effect independent of endothelial mechanisms, probably regulating calcium influx or release into or within the cell, the later demonstrated in mice.

  • 0 views
  • 19 Feb, 2024
  • 1 location
Evaluation of Post Operative Pain in Retreatment of Molars Using Different Irrigant

This study evaluates the efficacy of dexamethasone as a intracanal irrigant along with sodium hypochlorite 1% and 5.25% concentrations in post treatment pain for molar root canal retreatment.

root canal
  • 0 views
  • 19 Feb, 2024
  • 1 location
Safety and Anti-coronavirus Response of Suppression of Host Nucleotide Synthesis in Patients With COVID-19

This will be a phase 1a randomized, open label, multi-center study with approximately 24 subjects. All subjects will receive standard of care (SOC) per institutional guidelines for treatment of hospitalized patients with COVID-19 infection. In addition to SOC, the brequinar group will receive 5 daily doses of brequinar 100 mg.

fever
FIO2
malaise
covid-19
acute respiratory syndrome (sars)
  • 0 views
  • 19 Feb, 2024
  • 4 locations
Tocotrienol and Bevacizumab in Metastatic Colorectal Cancer

This double blind, randomized phase II trial will investigate whether the addition of tocotrienol will improve the effect and lower the toxicity of standard chemotherapy and bevacizumab. Half of the patients will receive tocotrienol and the other half placebo. Treatment is planned for a period of maximum six months and …

serum bilirubin level
disseminated cancer
bilateral oophorectomy
kidney function tests
tocotrienol
  • 0 views
  • 19 Feb, 2024
  • 1 location
Neoadjuvant RCT Versus CT for Patients With Locally Advanced Potentially Resectable Adenocarcinoma of the GEJ

This is a multicenter, prospective, randomized, stratified, controlled, open-label study comparing neoadjuvant radiochemotherapy with FLOT versus FLOT chemotherapy alone fr patients with locally advanced, potentially resectable adenocarcinoma of the gastroesophageal junction (GEJ)

docetaxel
aptt
progestogen
flot regimen
adenocarcinoma
  • 0 views
  • 19 Feb, 2024
  • 1 location
The Effects of Maxipost (BMS 204352) on Cerebral Hemodynamic and Headache in Healthy Volunteers and Migraine Patients  

Maxipost (BMS 204352) is a vasoactive molecule that causes vasodilation via the big calcium dependent potassium (BKCa) channel signaling pathway. Maxipost decreases the blood pressure and maxipost infusion causes headache in healthy volunteers.

maxipost
migraine
potassium
potassium channels
vasodilatation
  • 0 views
  • 19 Feb, 2024
  • 1 location