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Found 12 clinical trials
Quantifying Oxygen Utilization of Tumors Using Oxygen-Enhanced Molecular MRI

This trial looks to study the safety and feasibility of using oxygen-enhanced molecular MRI to understand how cancer cells use oxygen differently than normal cells. Cancer cells tend to utilize (or not utilize) oxygen differently than normal cells. By using the oxygen-enhanced molecular MRI, researchers will be able to create …

brain metastasis
brain metastases
brain tumor
cancer
metastasis
  • 0 views
  • 19 Feb, 2024
  • 1 location
Understanding Factors That Influence Electronic Cigarette Nicotine Delivery Through PET Imaging of Beta-2 Nicotinic Acetylcholine Receptors

The goal of this proposal is to test the overall hypothesis that e-cigarettes (ECs) provide efficient nicotine delivery to the brain and arterial blood in non-EC-nave smokers and e-cigarette users and that EC liquid characteristics modulate this effect. This study will test the hypothesis through complementary methods that include [ …

  • 0 views
  • 19 Feb, 2024
  • 1 location
Diffusion MRI for Head and Neck Cancer

The proposed study is to investigate the feasibility of using quantitative diffusion MRI (dMRI) methods for accurate and comprehensive assessment of treatment response. dMRI is a powerful tool to probe treatment-induced change in tumors. It is a unique in vivo imaging technique sensitive to cellular microstructures at the scale of …

chemoradiotherapy
chemoradiation therapy
squamous cell carcinoma of head and neck
head and neck cancer
neck cancer
  • 0 views
  • 19 Feb, 2024
  • 1 location
bpMRI and Risk Based Shared Clinical Decision Making in Prostate Cancer Diagnosis

Therefore, the primary objective of this trial is to compare if there is a difference between significant cancer detection rate in men undergoing prostate biopsies after MRI scan compared to men undergoing post-MRI prostate biopsies only after a shared decision-making based on prostate cancer risk estimation.

biopsy of prostate
cancer diagnosis
digital rectal examination
  • 0 views
  • 19 Feb, 2024
  • 4 locations
Hyperpolarized 13C Pyruvate MRI Scan in Predicting Tumor Aggressiveness in Patients With Localized Renal Tumor

This feasibility study will evaluate how well hyperpolarized 13C pyruvate magnetic resonance imaging (MRI) scan works in predicting tumor aggressiveness in patients with localized renal tumor. Hyperpolarized 13C pyruvate is a non-radioactive substance with potential usage in the diagnostic imaging of tumors.

renal neoplasm
aggressiveness
MRI
estimated creatinine clearance
abdominal mri
  • 0 views
  • 19 Feb, 2024
  • 1 location
PET Imaging of Cyclooxygenases in Dementia

Their heart function will be measured. Participants will have a magnetic resonance imaging (MRI) scan. The MRI scanner is a metal tube surrounded by a strong magnetic field. Participants will lie on a table that slides in and out of the tube.

huntington's chorea
positron emission tomography
neurological examination
neurodegenerative disorders
MRI
  • 0 views
  • 19 Feb, 2024
  • 1 location
Magnetic Resonance Imaging of the Brain and Stomach in Healthy Volunteers and Gastroparesis

The study is to lay the groundwork for non invasive imaging of the GI tract and the brain gut interaction

nausea
epigastric pain
vomit
gastroparesis
regurgitation
  • 0 views
  • 19 Feb, 2024
  • 1 location
Minocycline in MS: Confirmation of Benefit

This is an open-label, single-arm clinical trial. Trial participants will include men and women, aged 18-60 years who have had a first demyelinating event within the previous 180 days and who have brain magnetic resonance imaging (MRI) with at least two brain T2 lesions which are at least 3 mm …

demyelinating disorder
brain lesion
multiple symptoms
mri brain
demyelination
  • 0 views
  • 19 Feb, 2024
  • 1 location
7T Anatomo-functional Characterization of Structures in the Action Observation Network (7T-ATHENA)

Are different patterns of functional activation correlated to different clinical characteristics of CP patients?Participants will perform a 7 Tesla MRI scan, with a functional and anatomical dedicated protocol and will have a comprehensive clinical assessment before the MRI exam.

Accepts healthy volunteers
  • 0 views
  • 14 Feb, 2025
Advanced Geriatric Evaluation and Quality of Life in Colorectal Cancer Surgery

Colorectal cancer (CRC) disproportionately affects patients aged 70 years and older. Surgery is the main treatment modality for CRC, but is associated with increased risk of postoperative morbidity, disability and loss of health related quality of life (HRQL).Frailty is an age related state of functional decline and considered to be …

metastatic colorectal cancer
cancer surgery
colorectal cancer
  • 0 views
  • 19 Feb, 2024
  • 6 locations