McLean, Virginia Clinical Trials

A listing of McLean, Virginia clinical trials actively recruiting patient volunteers.

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Found 106 clinical trials
Metarrestin (ML-246) in Subjects With Metastatic Solid Tumors

Background Metastasis is the spread of cancer from one organ to a nonadjacent organ. It causes 90% of cancer deaths. No treatment specifically prevents or reduces metastasis. Researchers hope a new drug can help. It stops cancer cells from growing and spreading further and possibly shrink cancer lesions in distant …

blood tests
cancer
MRI
renal function
blood test
National Institutes of Health Clinical Center
 (6.4 away) Contact site
  • 0 views
  • 24 Nov, 2025
  • 1 location
Treatment of Moderate to Severe Lateral Canthal Lines and Glabellar Lines Alone or in Combination

This study is designed to evaluate the safety and efficacy of a single dose of QM1114-DP for the treatment of moderate to severe LCL and moderate to severe GL, alone or in combination.

Washington Institute of Dermatologic Laser Surgery
 (6.7 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +9 other locations
Chimney EndoVascular Aneurysm Sealing Of New Expanded Indication

Prospective, multi-center, non-randomized study with consecutive, eligible subject enrollment at each site, for the evaluation of the ChEVAS System for Endovascular Repair of Complex Abdominal Aortic Aneurysms.

MedStar Health Research Institute
 (7.9 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +2 other locations
SPRINT Peripheral Nerve Stimulation for the Treatment of Back Pain

The purpose of this study is to compare standard of care treatments for back pain to electrical stimulation. Electrical stimulation is delivering small amounts of electricity to the nerves in your low back. This study will use a device called the SPRINT Peripheral Nerve Stimulation (PNS) System. The SPRINT PNS …

low back pain
peripheral nerve stimulation
electrical stimulation
chronic pain
back pain
International Spine, Pain & Performance Center
 (7.6 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +1 other locations
Pilot Study to Evaluate the Effect of Nicotinamide Riboside on Immune Activation in Psoriasis

Background Psoriasis causes chronic inflammation in the body. Researchers want to see if a kind of vitamin B3 dietary supplement can help. This might lead to more treatment options. Objective To test if the dietary supplement nicotinamide riboside can improve immune system function in the blood and skin of people …

body mass index
niacin
chronic inflammation
psoriasis
urine test
National Institutes of Health Clinical Center
 (6.4 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • 1 location
A First-in-human Study Using BDC-1001 in Advanced and HER2-Expressing Solid Tumors

A first-in-human study using BDC-1001 in HER2 expressing advanced malignancies

gene amplification
cancer
advanced solid tumor
advanced malignant solid tumor
HER2
Bolt Investigative Site
 (6.5 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +6 other locations
A Safety Study of Oral Venetoclax in Combination With Intravenous Pembrolizumab in Adult Participants With Previously Untreated Non-Small Cell Lung Cancer (NSCLC) With High Programmed Cell Death Ligand-1 (PD-L1) Expression

Non-Small Cell Lung Cancer (NSCLC) is a solid tumor, a disease in which cancer cells form in the tissues of the lung. It is the most common form of lung cancer, accounting for around 85% of lung cancers. The purpose of this study is to evaluate the safety and efficacy …

cancer
blood test
non-small cell lung cancer
venetoclax
solid tumor
Virginia Cancer Specialists /ID# 214328
 (6.5 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +38 other locations
PB2452 in Ticagrelor-treated Patients With Uncontrolled Major or Life-Threatening Bleeding or Requiring Urgent Surgery or Invasive Procedure

This is a multi-center, open-label, prospective single-arm study of reversal of the antiplatelet effects of ticagrelor with PB2452 in patients who present with uncontrolled major or life-threatening bleeding or who require urgent surgery or invasive procedure. Approximately 200 patients will be enrolled at approximately 200 centers worldwide. Patients with reported …

systolic blood pressure
blood transfusion
postoperative hemorrhage
orthopedic surgery
ticagrelor
MedStar Health Research Institute
 (7.9 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +5 other locations
Phase 2 Clinical Trial of Crizotinib for Children and Adults With Neurofibromatosis Type 2 and Progressive Vestibular Schwannomas

Subjects with Neurofibromatosis Type 2 (NF2) and progressive vestibular schwannoma (VS) will be treated with crizotinib administered orally. Crizotinib will be taken continuously until disease progression or unacceptable toxicity, in continuous treatment cycles of 28 days each, for a maximum of 12 cycles.

nf2 gene
multiple meningiomas
neutrophil count
cataract
glioma
Children's National Medical Center (Site 775)
 (7.9 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +16 other locations
Virtual Reality Mobility Assessment of Functional Vision in Retinal Disease

Background The retina is a thin layer of tissue at the back of the eye. Retinal disease usually reduces a person s mobility because it affects how he or she moves through familiar and unfamiliar environments. Researchers want to see if a virtual reality (VR) tool can provide an easier …

National Institutes of Health Clinical Center
 (6.4 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +1 other locations