Houston, Texas Clinical Trials

A listing of Houston, Texas clinical trials actively recruiting patient volunteers.

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Found 94 clinical trials
An Efficacy and Safety Study of Ravulizumab in ALS Participants

The purpose of the study is to assess the efficacy and safety of ravulizumab for the treatment of adult participants with ALS.

riluzole
edaravone
vaccination
ravulizumab
Nerve & Muscle Center of Texas
 (4.3 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +6 other locations
ELUCIDATE: Enabling LUng Cancer IDentification Using folATE Receptor Targeting

This is a phase 3, multi-center, single dose, open-label, exploratory study in suspected lung cancer patients scheduled to undergo endoscopic or thoracic surgery per CT/PET/MRI or other imaging based on standard of care. This study aims to assess the efficacy of OTL38 and Near Infrared Imaging (NIR) at identifying pulmonary …

pulmonary resection
cancer
folic acid
wedge excision
wedge resection
MD Anderson Cancer Center
 (4.3 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +4 other locations
FT596 as a Monotherapy and in Combination With Anti-CD20 Monoclonal Antibodies

This is a Phase I dose-finding study of FT596 as monotherapy and in combination with Rituximab or Obinutuzumab in subjects with relapsed/refractory B-cell Lymphoma or Chronic Lymphocytic Leukemia. The study will consist of a dose-escalation stage and an expansion stage where participants will be enrolled into indication-specific cohorts.

lymphoma
chronic lymphocytic leukemia
b-cell lymphoma refractory
contraceptive use
obinutuzumab
MD Anderson Cancer Center
 (4.3 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +2 other locations
Early Feasibility Study: Fetoscopic NEOX Cord 1K Myelomeningocele (MMC) Repair

The purpose of this study is to test the feasibility of surgically covering myelomeningocele spina bifida spinal cord developmental defects using Neox Cord 1K, cryopreserved human umbilical cords, via a laparotomy-fetoscopic surgical approach. Intact repair of the defect, prevention of cerebral spinal fluid leakage and wound dehiscence will be assessed …

myelomeningocele
spina bifida
body mass index
kyphosis
spinal cord disease
The University of Texas Health Science Center at Houston
 (4.3 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • 1 location
A Study of ASTX030 (Cedazuridine in Combination With Azacitidine) in MDS CMML or AML

Study ASTX030-01 is designed to move efficiently from Phase 1 to Phase 3. Phase 1 consists of an open-label Dose Escalation Stage (Stage A) using multiple cohorts at escalating dose levels of oral cedazuridine and azacitidine (only one study drug will be escalated at a time) followed by a Dose …

azacitidine
dysplasia
myelodysplastic/myeloproliferative disease
ringed sideroblasts
chronic myeloid leukemia
MD Anderson Cancer Center
 (4.3 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +1 other locations
Avelumab and M6620 for the Treatment of DDR Deficient Metastatic or Unresectable Solid Tumors

This phase I/II trial studies the side effects and best dose of avelumab with M6620 in treating patients with deoxyribonucleic acid (DNA) damage repair (DDR) deficient solid tumors that have spread to other places in the body (metastatic) or cannot be removed by surgery (unresectable). DDR deficiency refers to a …

cancer therapy
estimated creatinine clearance
biopsy
ovarian failure
oral contraception
M D Anderson Cancer Center
 (4.3 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • 1 location
ATR Inhibitor BAY 1895344 Plus Niraparib Phase 1b Study in Advanced Solid Tumors and Ovarian Cancer

The purpose of the study is to test how well patients with advanced solid tumors and ovarian cancer respond to treatment with BAY1895344 in combination with niraparib. In addition researchers want to find for patients the optimal dose of BAY1895344 in combination with niraparib, how the drug is tolerated and …

niraparib
measurable disease
primary peritoneal carcinoma
solid tumour
prostate cancer
University of Texas MD Anderson Cancer Center
 (4.3 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +3 other locations
A First-in-human Study Using BDC-1001 in Advanced and HER2-Expressing Solid Tumors

A first-in-human study using BDC-1001 in HER2 expressing advanced malignancies

cancer
measurable disease
exhausted
advanced solid tumor
solid tumour
Bolt Investigative Site
 (4.3 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +6 other locations
Tipifarnib for the Treatment of Advanced Solid Tumors Lymphoma or Histiocytic Disorders With HRAS Gene Alterations a Pediatric MATCH Treatment Trial

This phase II pediatric MATCH trial studies how well tipifarnib works in treating patients with solid tumors that have spread to other places in the body (advanced), lymphoma, or histiocytic disorders that have HRAS genetic alterations. Tipifarnib may block the growth of cancer cells that have specific genetic changes in …

lymphoma
blood count
platelet transfusion
MRI
bone marrow infiltration
Baylor College of Medicine/Dan L Duncan Comprehensive Cancer Center
 (4.3 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +82 other locations
Use of an Educational Multimedia Tool Versus Routine Care for the Uptake of Postpartum LARC in High-Risk Pregnancies

The purpose of the study is to evaluate if the implementation of a multimedia based educational tool and regular reminders with shared decision-making will increase the rate of LARC uptake and retention in high risk pregnancy patients within 12 weeks of delivery and to study the rates of retention of …

high risk pregnancy
The University of Texas Health Science Center at Houston
 (4.3 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • 1 location