Dallas, Texas Clinical Trials

A listing of Dallas, Texas clinical trials actively recruiting patient volunteers.

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Found 70 clinical trials
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Texas Oncology - Baylor Sammons Cancer Center
 (1.8 away) Contact site
  • 0 views
  • 19 May, 2025
  • +19 other locations
A Study of Tirzepatide (LY3298176) Compared With Dulaglutide on Major Cardiovascular Events in Participants With Type 2 Diabetes

The purpose of the trial is to assess the efficacy and safety of tirzepatide to dulaglutide in participants with type 2 diabetes and increased cardiovascular risk.

body mass index
tirzepatide
dulaglutide
cardiovascular disease
Cardiovascular Research Institute of Dallas
 (7.5 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +650 other locations
A Study of Donanemab (LY3002813) in Participants With Early Alzheimer's Disease (TRAILBLAZER-ALZ 2)

The reason for this study is to see how safe and effective the study drug donanemab is in participants with early Alzheimer's disease.

flortaucipir
alzheimer's disease
positron emission tomography
mini-mental state examination
florbetapir
Baylor AT&T Memory Center
 (7.5 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +85 other locations
First-in-Human Study of XMT-1592 in Patients With Ovarian Cancer and NSCLC Likely to Express NaPi2b

Phase 1b, a study in high grade serous ovarian cancer and nonsmall cell lung cancer to evaluate the safety and clinical activity of the antibody-drug conjugate (ADC) XMT-1592.

cancer
measurable disease
primary peritoneal carcinoma
ovarian cancer
peritoneal cancer
Mary Crowley Cancer Research Center
 (0.9 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +2 other locations
THE ALIGN-AR PIVOTAL TRIAL: JenaValve Pericardial TAVR Aortic Regurgitation Study

To collect information about treatment for symptomatic severe Aortic Regurgitation (AR), which affects the aortic valve in the heart. Aortic regurgitation is a condition where aortic valve in the heart does not close tightly and allows some blood to leak back into the heart chamber. Symptoms of aortic regurgitation may …

aortic valve replacement
shortness of breath
fatigue
regurgitation
Baylor Scott & White Research Institute
 (0.9 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +9 other locations
A Study of CC-98633 BCMA-targeted Chimeric Antigen Receptor (CAR) T Cells in Subjects With Relapsed and/or Refractory Multiple Myeloma

This is a Phase 1, multicenter, open-label study of CC-98633, BCMA-Targeted NEX-T Chimeric Antigen Receptor (CAR) T Cells, in subjects with relapsed and/or refractory multiple myeloma. The study will consist of 2 parts: dose-escalation (Part A) and dose-expansion (Part B). The dose-escalation part (Part A) of the study is to …

proteasome inhibitor
immunotherapeutic agent
thalidomide
measurable disease
bcma
UT Southwestern Medical Center
 (3.4 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +8 other locations
Testing the Addition of Radiotherapy to the Usual Treatment (Chemotherapy) for Patients With Esophageal and Gastric Cancer That Has Spread to a Limited Number of Other Places in the Body

This phase III trial studies how well the addition of radiotherapy to the usual treatment (chemotherapy) works compared to the usual treatment alone in treating patients with esophageal and gastric cancer that has spread to a limited number of other places in the body (oligometastatic disease). Radiotherapy uses high energy …

pathologic stage iv gastric cancer ajcc v8
ct scan
lymphadenopathy
MRI
hiv test
UT Southwestern/Simmons Cancer Center-Dallas
 (3.4 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +254 other locations
Tipifarnib for the Treatment of Advanced Solid Tumors Lymphoma or Histiocytic Disorders With HRAS Gene Alterations a Pediatric MATCH Treatment Trial

This phase II pediatric MATCH trial studies how well tipifarnib works in treating patients with solid tumors that have spread to other places in the body (advanced), lymphoma, or histiocytic disorders that have HRAS genetic alterations. Tipifarnib may block the growth of cancer cells that have specific genetic changes in …

lymphoma
blood count
platelet transfusion
MRI
bone marrow infiltration
UT Southwestern/Simmons Cancer Center-Dallas
 (3.4 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +82 other locations
Phase 2 Clinical Trial of Crizotinib for Children and Adults With Neurofibromatosis Type 2 and Progressive Vestibular Schwannomas

Subjects with Neurofibromatosis Type 2 (NF2) and progressive vestibular schwannoma (VS) will be treated with crizotinib administered orally. Crizotinib will be taken continuously until disease progression or unacceptable toxicity, in continuous treatment cycles of 28 days each, for a maximum of 12 cycles.

measurable disease
glioma
cataract
neurofibroma
schwartz
Childrens Medical Center - Univ. of Texas SW (Site 917)
 (4.8 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +16 other locations
Multicenter Clinical Trial of a Phakic Implantable Collamer Lens (ICL)

This objective of this study is to evaluate the safety, and to collect supportive data on effectiveness of the EVO/EVO+ Visian Implantable Collamer Lens (ICL) in study participants who have a diagnosis of myopia or myopia with astigmatism. Primary study analysis will be evaluated when 300 primary eyes complete 6 …

severe myopia
myopia
astigmatism
Key-Whitman Eye Center
 (9.7 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +13 other locations