Simpsonville, South Carolina Clinical Trials

A listing of Simpsonville, South Carolina clinical trials actively recruiting patient volunteers.

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Found 40 clinical trials
A Study to Test the Efficacy and Safety of Bimekizumab in Study Participants With Moderate to Severe Hidradenitis Suppurativa

The purpose of the study is to test the efficacy and safety of bimekizumab in study participants with moderate to severe hidradenitis suppurativa (HS)

hidradenitis
antibiotics
abscess
bimekizumab
antibiotic therapy
Hs0004 50236
 (8.1 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +15 other locations
SAR408701 Versus Docetaxel in Previously Treated Carcinoembryonic Antigen-related Cell Adhesion Molecule 5 (CEACAM5) Positive Metastatic Non-squamous Non-small Cell Lung Cancer Patients

Primary Objectives: Study is designed with two primary endpoints that will be analyzed on randomized participants at the time of the cutoff date for each given analysis (progressive free survival [PFS] and overall survival [OS]). Study success is defined either on PFS or OS The primary objective is to determine …

lung cancer
cancer
measurable disease
stage iv non-small cell lung cancer
docetaxel
Investigational Site Number 8400014
 (8.1 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +168 other locations
Study of AMG 509 in Subjects With Metastatic Castration-Resistant Prostate Cancer

Evaluate the safety and tolerability of AMG 509 in adult subjects and determine the maximum tolerated dose (MTD) or recommended phase 2 dose (RP2D).

bilateral orchidectomy
serum testosterone
cancer
gonadotropin
enzalutamide
Research Site
 (7.0 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +3 other locations
A Safety Study of Oral Venetoclax in Combination With Intravenous Pembrolizumab in Adult Participants With Previously Untreated Non-Small Cell Lung Cancer (NSCLC) With High Programmed Cell Death Ligand-1 (PD-L1) Expression

Non-Small Cell Lung Cancer (NSCLC) is a solid tumor, a disease in which cancer cells form in the tissues of the lung. It is the most common form of lung cancer, accounting for around 85% of lung cancers. The purpose of this study is to evaluate the safety and efficacy …

measurable disease
cancer
lymphoma
epidermal growth factor receptor
small cell lung cancer
Prisma Health /ID# 217946
 (7.0 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +38 other locations
Tipifarnib for the Treatment of Advanced Solid Tumors Lymphoma or Histiocytic Disorders With HRAS Gene Alterations a Pediatric MATCH Treatment Trial

This phase II pediatric MATCH trial studies how well tipifarnib works in treating patients with solid tumors that have spread to other places in the body (advanced), lymphoma, or histiocytic disorders that have HRAS genetic alterations. Tipifarnib may block the growth of cancer cells that have specific genetic changes in …

refractory non-hodgkin lymphoma
cancer treatment
stem cell infusion
corticosteroids
hras gene
BI-LO Charities Children's Cancer Center
 (7.0 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +82 other locations
International Collaborative Gaucher Group (ICGG) Gaucher Disease Registry & Pregnancy Sub-registry

The ICGG Gaucher Registry is an ongoing, international multi-center, strictly observational program that tracks the routine clinical outcomes for patients with Gaucher disease, irrespective of treatment status. No experimental intervention is involved; patients in the Registry undergo clinical assessments and receive care as determined by the patient's treating physician. The …

eliglustat
gaucher disease
deficiency
imiglucerase
Investigational Site Number 840055
 (7.0 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +220 other locations
Mucopolysaccharidosis I (MPS I) Registry

The Mucopolysaccharidosis I (MPS I) Registry is an ongoing, observational database that tracks the outcomes of patients with MPS I. The data collected by the MPS I Registry will provide information to better characterize the natural history and progression of MPS I as well as the clinical responses of patients …

Investigational Site Number 840055
 (7.0 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +135 other locations
Pompe Disease Registry

The Pompe Registry is an ongoing, international multi-center, strictly observational program that tracks the routine clinical outcomes for patients with Pompe disease, irrespective of treatment status. No experimental intervention is involved; patients in the Registry undergo clinical assessments and receive care as determined by the patient's treating physician. The objectives …

gaa gene
glycogen storage disease type ii
myozyme
deficiency
replacement therapy
Investigational Site Number 840055
 (7.0 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +190 other locations
Fabry Disease Registry & Pregnancy Sub-registry

The Fabry Registry is an ongoing, international multi-center, strictly observational program that tracks the routine clinical outcomes for patients with Fabry disease, irrespective of treatment status. No experimental intervention is involved; patients in the Registry undergo clinical assessments and receive care as determined by the patient's treating physician. The primary …

alpha-galactosidase
fabry's disease
agalsidase beta
deficiency
fabrazyme
Investigational Site Number 840055
 (7.0 away) Contact site
  • 0 views
  • 05 Aug, 2024
  • +136 other locations
NCI COVID-19 in Cancer Patients NCCAPS Study

This study collects blood samples, medical information, and medical images from patients who are being treated for cancer and have a positive test for SARS CoV-2, the new coronavirus that causes the disease called COVID-19. Collecting blood samples, medical information, and medical images may help researchers determine how COVID-19 affects …

hematologic malignancy
cancer
acute respiratory syndrome (sars)
antibody test
cancer treatment
BI-LO Charities Children's Cancer Center
 (7.0 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +575 other locations