Rockledge, Pennsylvania Clinical Trials

A listing of Rockledge, Pennsylvania clinical trials actively recruiting patient volunteers.

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Found 64 clinical trials
Safety and Anti-coronavirus Response of Suppression of Host Nucleotide Synthesis in Patients With COVID-19

This will be a phase 1a randomized, open label, multi-center study with approximately 24 subjects. All subjects will receive standard of care (SOC) per institutional guidelines for treatment of hospitalized patients with COVID-19 infection. In addition to SOC, the brequinar group will receive 5 daily doses of brequinar 100 mg.

myalgia
malaise
pao2
dyspnea
SARS
Temple University
 (5.7 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +3 other locations
UPENN Case Test Trial 13 (Do Not Make Any Changes)

UPENN Case Test Trial 13 (Do Not Make Any Changes)

Abington Neurological Associates- Site Number : 8401065
 (4.3 away) Contact site
  • 0 views
  • 15 May, 2025
  • 1 location
Influence of Cooling Duration on Efficacy in Cardiac Arrest Patients

A multicenter, randomized, adaptive allocation clinical trial to determine if increasing durations of induced hypothermia are associated with an increasing rate of good neurological outcomes and to identify the optimal duration of induced hypothermia for neuroprotection in comatose survivors of cardiac arrest.

hypothermia
resuscitation
coma
induced hypothermia
cardiac arrest
Temple University Hospital
 (5.7 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +12 other locations
A Study of Tirzepatide (LY3298176) Compared With Dulaglutide on Major Cardiovascular Events in Participants With Type 2 Diabetes

The purpose of the trial is to assess the efficacy and safety of tirzepatide to dulaglutide in participants with type 2 diabetes and increased cardiovascular risk.

cardiovascular disease
tirzepatide
body mass index
dulaglutide
Northeast Endocrine Metabolic Associates
 (4.7 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +650 other locations
Durvalumab With or Without Olaparib as Maintenance Therapy After First-Line Treatment of Advanced and Recurrent Endometrial Cancer

A study to assess the efficacy and safety of durvalumab in combination with platinum-based chemotherapy (paclitaxel + carboplatin) followed by maintenance durvalumab with or without olaparib for patients with newly diagnosed advanced or recurrent endometrial cancer.

adjuvant
measurable disease
carcinoma
cancer
endometrial carcinoma
Research Site
 (10.0 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +94 other locations
A Study of Donanemab (LY3002813) in Participants With Early Alzheimer's Disease (TRAILBLAZER-ALZ 2)

The reason for this study is to see how safe and effective the study drug donanemab is in participants with early Alzheimer's disease.

mini-mental state examination
florbetapir
alzheimer's disease
flortaucipir
positron emission tomography
Clinical Trial Center, LLC, Psychiatry
 (2.1 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +85 other locations
Study of AMG 509 in Subjects With Metastatic Castration-Resistant Prostate Cancer

Evaluate the safety and tolerability of AMG 509 in adult subjects and determine the maximum tolerated dose (MTD) or recommended phase 2 dose (RP2D).

castration-resistant prostate cancer
cancer
dexamethasone
neutrophil count
metastasis
Research Site
 (9.3 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +3 other locations
Accelerometer Sensing for Micra AV Study

The purpose of the AccelAV Study is to characterize chronic AV synchrony in subjects implanted with MicraTM AV device. This study will be conducted upon market approval of the MicraTM AV Transcatheter Pacing System.

atrioventricular block
Thomas Jefferson University
 (9.3 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +5 other locations
Chimney EndoVascular Aneurysm Sealing Of New Expanded Indication

Prospective, multi-center, non-randomized study with consecutive, eligible subject enrollment at each site, for the evaluation of the ChEVAS System for Endovascular Repair of Complex Abdominal Aortic Aneurysms.

Cooper University Hospital
 (10.0 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +2 other locations
A Study of SY 5609 a Selective CDK7 Inhibitor in Advanced Solid Tumors

This is a dose escalation study and will be the first to administer SY-5609 alone to humans with select advanced solid tumors and in combination with Fulvestrant to patients with HR positive, HER2-negative breast cancer.

measurable disease
cancer
health screening
stage iv breast cancer
gonadotropin
Sidney Kimmel Cancer Center
 (9.3 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +4 other locations