Pittsburgh, Pennsylvania Clinical Trials

A listing of Pittsburgh, Pennsylvania clinical trials actively recruiting patient volunteers.

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Found 58 clinical trials
Clinical Trial for Surgery of the Ulnar Nerve (SUN) at the Elbow

This research is studying two surgical procedures in a large group of people to learn about how well these procedures work as a treatment for ulnar neuropathy at the elbow (UNE). Researchers want to see which surgery is more helpful for people with ulnar neuropathy. This research will determine if …

University of Pittsburgh Medical Center
 (2.6 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +9 other locations
Safety and Efficacy of IMC-F106C as a Single Agent and in Combination With Checkpoint Inhibitors

IMC-F106C is an immune-mobilizing T cell receptor against cancer (ImmTAC ) designed for the treatment of cancers positive for the tumor-associated antigen PRAME. This is a first-in-human trial designed to evaluate the safety and efficacy of IMC-F106C in adult patients who have the appropriate HLA-A2 tissue marker and whose cancer …

UPMC Hillman Cancer Center
 (1.9 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +9 other locations
A Study of SBT6050 in Patients With Advanced HER2 Expressing Solid Tumors

A first-in-human (FIH) study using SBT6050 in HER2 expressing advanced malignancies

cancer
solid tumor
measurable disease
pembrolizumab
solid tumour
Investigative Site
 (1.9 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +2 other locations
The EMS Sleep Health Study: A Randomized Controlled Trial

The experiment seeks to determine the impact of a sleep health and fatigue education and training program on diverse indicators of sleep and fatigue among Emergency Medical Services (EMS) personnel. The overarching goals of this research study are to [1] enhance our understanding of the relationships between shift work, sleep, …

fatigue
University of Pittsburgh
 (2.4 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • 1 location
Influence of Cooling Duration on Efficacy in Cardiac Arrest Patients

A multicenter, randomized, adaptive allocation clinical trial to determine if increasing durations of induced hypothermia are associated with an increasing rate of good neurological outcomes and to identify the optimal duration of induced hypothermia for neuroprotection in comatose survivors of cardiac arrest.

resuscitation
cardiac arrest
coma
hypothermia
life support
University of Pittsburgh Medical Center
 (2.6 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +12 other locations
A Study of Tirzepatide (LY3298176) Compared With Dulaglutide on Major Cardiovascular Events in Participants With Type 2 Diabetes

The purpose of the trial is to assess the efficacy and safety of tirzepatide to dulaglutide in participants with type 2 diabetes and increased cardiovascular risk.

body mass index
tirzepatide
dulaglutide
cardiovascular disease
Preferred Primary Care Physicians
 (9.5 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +650 other locations
Testing Legally Feasible Options: Study 1

The overall aim of this research is to experimentally evaluate different, legally-viable approaches to reducing the impact of the point-of-sale (POS) retail environment on adolescent tobacco use risk. This study will be investigating the regulations for four classes of tobacco products (cigarettes, e-cigarettes, smokeless tobacco, little cigars/cigarillos). Study 1 (study …

tobacco product
RAND
 (2.6 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • 1 location
Semantic Feature Analysis Treatment for Aphasia

This randomized controlled comparative effectiveness study examines manipulation of a key component of an established and efficacious treatment for naming impairments in aphasia, along with cognitive and brain correlates of treatment success. Study participants will be randomly assigned to one of two treatment conditions comparing two different versions of Semantic …

brain imaging
aphasia
stroke
functional brain imaging
manipulation
VA Pittsburgh Healthcare System
 (3.4 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • 1 location
ELUCIDATE: Enabling LUng Cancer IDentification Using folATE Receptor Targeting

This is a phase 3, multi-center, single dose, open-label, exploratory study in suspected lung cancer patients scheduled to undergo endoscopic or thoracic surgery per CT/PET/MRI or other imaging based on standard of care. This study aims to assess the efficacy of OTL38 and Near Infrared Imaging (NIR) at identifying pulmonary …

lung cancer
wedge excision
thoracic surgery
infrared imaging
cancer
University of Pittsburgh Medical Center
 (1.9 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +4 other locations
A First-in-human Study Using BDC-1001 in Advanced and HER2-Expressing Solid Tumors

A first-in-human study using BDC-1001 in HER2 expressing advanced malignancies

solid tumor
measurable disease
metastasis
HER2
solid tumour
Bolt Investigative Site
 (2.6 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +6 other locations